4-Hydroxymethyl Loratadine

4-Hydroxymethyl Loratadine Suppliers list

Company Name:	Chemsky（shanghai）International Co.,Ltd.
Tel:	021-50135380
Email:	shchemsky@sina.com

Company Name:	S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel:	0755-4000505016 13380397412
Email:	3001272453@qq.com

Company Name:	Quality Control Solutions Ltd.
Tel:	0755-66853366 13670046396
Email:	orders@qcsrm.com

4-Hydroxymethyl Loratadine manufacturers

4-Hydroxymethyl Loratadine Basic information

Product Name:	4-Hydroxymethyl Loratadine
Synonyms:	ethyl 4-[8-chloro-4-(hydroxymethyl)-5,6-dihydrobenzo[4,5]cyclohepta[1,2-b]pyridin-11-ylidene]piperidine-1-carboxylate;Loratadine 4-Hydroxymethyl Impurity (USP);4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Este;4-[8-Chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester;Ethyl 4-[8-chloro-5,6-dihydro-4-(hydroxy methyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidine carboxylate;Loratadine Impurity 4;Loratadine Impurity 23;1-Piperidinecarboxylic acid, 4-[8-chloro-5,6-dihydro-4-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-, ethyl ester
CAS:	609806-40-8
MF:	C23H25ClN2O3
MW:	412.91
EINECS:
Product Categories:	Metabolites & Impurities;Pharmaceuticals;Intermediates & Fine Chemicals
Mol File:	609806-40-8.mol

4-Hydroxymethyl Loratadine Chemical Properties

Melting point	73-75°C
Boiling point	594.2±50.0 °C(Predicted)
density	1.301±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
form	Solid
pka	13.56±0.10(Predicted)
color	Pale Yellow
Stability:	Hygroscopic
InChI	InChI=1S/C23H25ClN2O3/c1-2-29-23(28)26-11-8-15(9-12-26)21-19-6-4-18(24)13-16(19)3-5-20-17(14-27)7-10-25-22(20)21/h4,6-7,10,13,27H,2-3,5,8-9,11-12,14H2,1H3
InChIKey	BCKYTUFUNAGTDV-UHFFFAOYSA-N
SMILES	N1(C(OCC)=O)CC/C(=C2\C3=NC=CC(CO)=C3CCC3=CC(Cl)=CC=C3\2)/CC1

Safety Information

MSDS Information

4-Hydroxymethyl Loratadine Usage And Synthesis

Chemical Properties	Light-Yellow Solid
Uses	A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor.
Definition	ChEBI: 4-Hydroxymethyl Loratadine is a benzocycloheptapyridine.

4-Hydroxymethyl Loratadine Preparation Products And Raw materials

Tag:4-Hydroxymethyl Loratadine(609806-40-8) Related Product Information

Loratadine N-Methyl Desloratadine Loratadine Loratadine 2-Chloro IMpurity Desloratadine N-Hydroxypiperidine N-ForMyl Desloratadine 8-Dechloro-10-chloro Loratadine 8-Dechloro-7-chloro Loratadine 8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one Loratadine Impurity 15 8-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ol Loratadine Impurity 13 Loratadine Impurity 13 Loratadine Impurity 17 3-Hydroxy loratadine Loratadine Impurity 8 (1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride 4,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one (Loratadine Impurity)