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LGM Pharma
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1-(800)-881-8210 |
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Product Name:Nitracrine
CAS:4533-39-5
Purity:Typically NLT 98%
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BOC Sciences
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1-631-485-4226; 16314854226 |
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info@bocsci.com |
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Product Name:Nitracrine
CAS:4533-39-5
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| Company Name: |
MedChemexpress LLC
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021-58955995 |
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sales@medchemexpress.cn |
| Products Intro: |
Product Name:Nitracrine
CAS:4533-39-5
Purity:400RMB/1mg Package:>98%
|
Nitracrine manufacturers
- Nitracrine
-
- $1980.00
-
2026-05-21
- CAS:4533-39-5
- Purity:
- Supply Ability: 10g
|
| | Nitracrine Basic information |
| Product Name: | Nitracrine | | Synonyms: | Nitracrine;3-(dimethylamino)propyl-(1-nitroacridin-9-yl)amine;N',N'-dimethyl-N-(1-nitroacridin-9-yl)propane-1,3-diamine;1,3-Propanediamine, N1,N1-dimethyl-N3-(1-nitro-9-acridinyl)- | | CAS: | 4533-39-5 | | MF: | C18H20N4O2 | | MW: | 324.382 | | EINECS: | | | Product Categories: | | | Mol File: | 4533-39-5.mol |  |
| | Nitracrine Chemical Properties |
| Melting point | 134-135° | | Boiling point | 462.71°C (rough estimate) | | density | 1.2155 (rough estimate) | | refractive index | 1.6700 (estimate) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | pKa1 6.45; pKa2 8.8(at 25℃) | | form | Solid | | color | Brown to reddish brown |
| | Nitracrine Usage And Synthesis |
| Uses | Nitracrine inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine, a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine has cytotoxicity towards most cells[1][2][3]. | | Definition | ChEBI: Nitracrine is a member of acridines. | | References | [1] Wilson WR, et al. Selective toxicity of nitracrine to hypoxic mammalian cells. Br J Cancer. 1984 Feb;49(2):215-23. DOI:10.1038/bjc.1984.34
[2] Gniazdowski M, et al. Nitracrine and its congeners--an overview. Gen Pharmacol. 1995 May;26(3):473-81. DOI:10.1016/0306-3623(94)00143-b
[3] Daghastanli NA, et al. Cytotoxicity of nitroheterocyclic compounds, quinifuryl and nitracrine, towards leukaemic and normal cells on the dark and under illumination with visible light. J Photochem Photobiol B. 2004 Jul 19;75(1-2):27-32. DOI:10.1016/j.jphotobiol.2004.04.005 |
| | Nitracrine Preparation Products And Raw materials |
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