Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester

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Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester Suppliers list
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Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester manufacturers

  • NAAA-IN-1
  • NAAA-IN-1 pictures
  • $2140.00
  • 2026-05-11
  • CAS:1439366-66-1
  • Purity:
  • Supply Ability: 10g
Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester Basic information
Product Name:Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester
Synonyms:Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester;NAAA-IN-1
CAS:1439366-66-1
MF:C18H17NO4
MW:311.33
EINECS:
Product Categories:
Mol File:1439366-66-1.mol
Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester Structure
Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester Chemical Properties
Boiling point 524.9±50.0 °C(Predicted)
density 1.27±0.1 g/cm3(Predicted)
pka10.13±0.40(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester Usage And Synthesis
UsesNAAA-IN-1 (Compound 1) is a potent and selective inhibitor of NAAA with an IC50 of 7 nM. NAAA is a cysteine amidase which preferentially hydrolyzes the endogenous biolipids palmitoylethanolamide (PEA) and oleoylethanolamide (OEA). NAAA-IN-1 has the potential for the research of inflammation and pain[1].
References[1] Malamas MS, et al. Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitors. Bioorg Med Chem. 2020 Jan 1;28(1):115195. DOI:10.1016/j.bmc.2019.115195
Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester Preparation Products And Raw materials
Tag:Carbamic acid, N-[(2S,3R)-2-methyl-4-oxo-3-oxetanyl]-, [1,1'-biphenyl]-4-ylmethyl ester(1439366-66-1) Related Product Information
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