3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- manufacturers
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| | 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Basic information |
| | 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Chemical Properties |
| Melting point | 314 °C(Solv: acetonitrile (75-05-8)) | | Boiling point | 630.5±55.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | pka | 6.65±0.15(Predicted) |
| | 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Usage And Synthesis |
| Uses | α-Glucosidase-IN-9 (compound 7) is a potent α-glucosidase inhibitor, with an IC50 of 55.6 μM. α-Glucosidase-IN-9 can be used for type II diabetes research[1]. | | IC 50 | Glucosidase | | References | [1] Ali M, et al. Synthesis, in vitro and in silico screening of 2-amino-4-aryl-6-(phenylthio) pyridine-3,5-dicarbonitriles as novel α-glucosidase inhibitors. Bioorg Chem. 2020 Jul;100:103879. DOI:10.1016/j.bioorg.2020.103879 |
| | 3,5-Pyridinedicarbonitrile, 2-amino-4-(4-hydroxyphenyl)-6-(phenylthio)- Preparation Products And Raw materials |
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