Hydrazinecarbothioamide, 2-(1-ethyl-5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-[4-(trifluoromethyl)phenyl]- manufacturers
- HSV-1/HSV-2-IN-1
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- $2500.00
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2026-05-11
- CAS:2490468-31-8
- Purity:
- Supply Ability: 10g
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| | Hydrazinecarbothioamide, 2-(1-ethyl-5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-[4-(trifluoromethyl)phenyl]- Basic information |
| | Hydrazinecarbothioamide, 2-(1-ethyl-5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-[4-(trifluoromethyl)phenyl]- Chemical Properties |
| Boiling point | 485.6±55.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | pka | 8.40±0.20(Predicted) |
| | Hydrazinecarbothioamide, 2-(1-ethyl-5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-[4-(trifluoromethyl)phenyl]- Usage And Synthesis |
| Uses | HSV-1/HSV-2-IN-1 (compound 7d) is a HSV-1 and HSV-2 inhibitor, with EC50s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK- KOS ACVr and vaccinia virus in human embryonic lung fibroblast cell cultures[1]. | | IC 50 | HSV-1; HSV-2 | | References | [1] Sevinli ZS, et, al. Synthesis, molecular modeling and antiviral activity of novel 5-fluoro-1H-indole-2,3-dione 3-thiosemicarbazones. Bioorg Chem. 2020 Nov;104:104202. DOI:10.1016/j.bioorg.2020.104202 |
| | Hydrazinecarbothioamide, 2-(1-ethyl-5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-N-[4-(trifluoromethyl)phenyl]- Preparation Products And Raw materials |
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