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BOC Sciences |
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1-631-485-4226; 16314854226 |
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info@bocsci.com |
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| | It 143-a Basic information |
| Product Name: | It 143-a | | Synonyms: | 4-Pyridinol, 2-(10-hydroxy-3,5,7,9,11,13-hexamethyl-2,5,7,11,13-pentadecapentaenyl)-5,6-dimethoxy-3-methyl- (9CI);2-(10-hydroxy-3,5,7,9,11,13-hexamethyl-2,5,7,11,13-pentadecapentaenyl)-5,6-dimethoxy-3-methyl-4-pyridinol;It 143-a | | CAS: | 183485-32-7 | | MF: | C29H43NO4 | | MW: | 469.66 | | EINECS: | | | Product Categories: | | | Mol File: | 183485-32-7.mol |  |
| | It 143-a Chemical Properties |
| Boiling point | 658.8±55.0 °C(Predicted) | | density | 1.027±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 5.22±0.33(Predicted) | | form | An oil |
| | It 143-a Usage And Synthesis |
| Description | IT-143A is a bacterial metabolite originally isolated from Streptomyces sp. IT-143. It is active against the bacterium M. luteus (MIC = 6.25 μg/ml) and the fungi A. fumigatus and T. rubrum in vitro (MICs = 12.5-25 μg/ml). | | Uses | IT-143A is an antibiotic, that exhibits antibacterial and antifungal activity against Micrococcus luteus and Aspergillus fumigatus with MIC of 6.25-25 μg/mL. IT-143A inhibits growth of cancer cell KB with an IC50 of 0.36 ng/mL[1]. | | References | [1] Urakawa A, et al., IT-143-A and B, novel piericidin-group antibiotics produced by Streptomyces sp. J Antibiot (Tokyo). 1996 Oct;49(10):1052-5. DOI:10.7164/antibiotics.49.1052 |
| | It 143-a Preparation Products And Raw materials |
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