roemerine manufacturers
- Roemerine
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- $98.00
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2026-05-11
- CAS:548-08-3
- Purity: 99.51%
- Supply Ability: 10g
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| | roemerine Basic information |
| Product Name: | roemerine | | Synonyms: | roemerine;(-)-N-Methylanonaine;(-)-Roemerine【alkaloid】;(6aR)-6-Methyl-1,2-(methylenedioxy)-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline;[7aR,(-)]-6,7,7a,8-Tetrahydro-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline;Remerine【alkaloid】;Roemerine【alkaloid】;(-)-Remerine | | CAS: | 548-08-3 | | MF: | C18H17NO2 | | MW: | 279.33 | | EINECS: | | | Product Categories: | | | Mol File: | 548-08-3.mol |  |
| | roemerine Chemical Properties |
| Melting point | 102-103℃ | | Boiling point | 424.0±34.0 °C(Predicted) | | density | 1.269±0.06 g/cm3 (20 ºC 760 Torr) | | solubility | Chloroform: soluble | | form | A solid | | pka | 7.87±0.20(Predicted) | | color | White to off-white |
| | roemerine Usage And Synthesis |
| Uses | Roemerine is an (-)-aporphine type of alkaloid which has been shown to possess significant antibacterial activity against Escheria Coli. | | Definition | ChEBI: Remerin is an isoquinoline alkaloid. | | in vivo | Roemerine (30 mg/kg, i.p., once every three days for 30 days) significantly inhibited tumor growth in the prostate cancer BALB/C nude mouse model (established by subcutaneous implantation of RM-1 cells)[2].
Roemerine (20 mg/kg, i.p., once daily for 2 days) increases survival and reduced bacterial loads in multiple organs in the MRSA XJ75302-induced sepsis BALB/C mouse model[5]. | Animal Model: | Prostate cancer BALB/C nude mouse model (established by subcutaneous implantation of RM-1 cells)[3] | | Dosage: | 30 mg/kg | | Administration: | Intraperitoneal injection (i.p.), once every three days for 30 days | | Result: | Significantly reduced tumor volume and weight in the experimental group (P < 0.05), with an inhibition rate of 41.2%. |
| Animal Model: | MRSA XJ75302-induced sepsis BALB/C mouse model[5] | | Dosage: | 20 mg/kg | | Administration: | Intraperitoneal injection (i.p.), once daily, for 2 days | | Result: | Increased the 7-day survival rate of mice to 58.3% (p < 0.05) and reduced bacterial loads in the liver (4.71 to 4.38 log CFU/mL), kidney (4.37 to 3.79 log CFU/mL), heart (5.44 to 3.76 log CFU/mL), and blood (6.52 to 4.55 log CFU/mL).
Note: CFU/mL represents the number of bacteria per milliliter of culture medium or tissue sample that can form colonies (CFU, Colony-Forming Units). |
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| | roemerine Preparation Products And Raw materials |
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