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ChemeGen |
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18818260767 |
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2625930290@qq.com |
| Company Name: |
InvivoChem |
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13549236410 |
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sales@invivochem.cn |
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| | althiomycin Basic information |
| Product Name: | althiomycin | | Synonyms: | althiomycin;N-[1-[4-[(2,5-Dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl]-4,5-dihydrothiazol-2-yl]-2-hydroxyethyl]-2-[(hydroxyimino)methyl]-4-thiazolecarboxamide;116-A;Matamycin;Nsc 102809;4-Thiazolecarboxamide, N-[1-[(4S)-4-[(2,5-dihydro-4-methoxy-2-oxo-1H-pyrrol-1-yl)carbonyl]-4,5-dihydro-2-thiazolyl]-2-hydroxyethyl]-2-[(E)-(hydroxyimino)methyl]-;NS-102809 | | CAS: | 12656-40-5 | | MF: | C16H17N5O6S2 | | MW: | 439.47 | | EINECS: | | | Product Categories: | | | Mol File: | 12656-40-5.mol |  |
| | althiomycin Chemical Properties |
| Melting point | 172-174 °C (decomp) | | density | 1.72±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | pka | 9.67±0.10(Predicted) | | form | A crystalline solid |
| | althiomycin Usage And Synthesis |
| Uses | Althiomycin is a polyketide synthase-derived thiazole antibiotic originally isolated from S. althioticus. It is active against Gram-positive bacteria, including S. aureus, S. epidermidis, and S. pyogenes (MICs=25, 25, and 3.1 μg/mL, respectively).2 Althiomycin inhibits protein synthesis in E. coli when used at concentrations of 1 and 10 μg/mL but not in isolated rabbit reticulocytes at 100 μg/mL. | | References | [1] Gerc, et al. The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin. PLoS One 7(9), e44673 (2012). |
| | althiomycin Preparation Products And Raw materials |
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