N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide

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N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Basic information
Product Name:N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide
Synonyms:N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide
CAS:2417718-26-2
MF:C25H19F3N2O
MW:420.43
EINECS:
Product Categories:
Mol File:2417718-26-2.mol
N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Structure
N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Chemical Properties
Boiling point 583.3±50.0 °C(Predicted)
density 1.259±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka13.30±0.46(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Usage And Synthesis
Uses(R)-VT104 is the R-enantiomer of VT104. (R)-VT104 shows an IC50 value of 0.1-1 μΜ for firefly luciferase. VT104 is an orally active and pan-TEAD auto-palmitoylation inhibitor[1].
References[1] Konradi, Andrei W, et al. Preparation of substituted naphthalene-2-carboxamide derivatives useful for treatment of cancer. WO2020097389.
N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide Preparation Products And Raw materials
Tag:N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide(2417718-26-2) Related Product Information
VT-105 2-Naphthalenecarboxamide, N-[(1S)-1-(6-amino-2-pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]- N-[(1R)-1-(2-Pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-2-naphthalenecarboxamide 2-Naphthalenecarboxamide, N-[(1S)-1-(2-pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]- Anti-Aging Compound Library 1H-Pyrrolo[2,3-b]pyridine-3-carboxamide, N-[4-(hydroxymethyl)-3-(phenylmethyl)-2(3H)-thiazolylidene]-, [N(Z)]-