| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:S1R agonist 1 hydrochloride
CAS:242487-82-7
Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
|
| Tel: |
010-60605840 |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:S1R agonist 1 hydrochloride
CAS:242487-82-7
Purity:>=99% Package:5mg;100mg;50mg;10mg;25mg
|
S1R agonist 1 hydrochloride manufacturers
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| | S1R agonist 1 hydrochloride Basic information |
| | S1R agonist 1 hydrochloride Chemical Properties |
| Melting point | 170-172 °C | | Boiling point | 159-162 °C(Press: 0.1 mmHg) | | form | Solid | | color | White to off-white |
| | S1R agonist 1 hydrochloride Usage And Synthesis |
| Uses | S1R agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. S1R agonist 1 hydrochloride exhibits neuroprotection against ROS and NMDA-induced neurotoxicity[1]. | | in vivo | S1R agonist 1 (Compound 6b; 0.1-50 μM; 120 h) hydrochloride induces the death of 4 Zebrafish embryos out of 8 at 10 μM[1]. | | References | [1] Linciano P, et al. Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents. Eur J Med Chem. 2023 Mar 5;249:115163. DOI:10.1016/j.ejmech.2023.115163 |
| | S1R agonist 1 hydrochloride Preparation Products And Raw materials |
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