3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid

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3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid Basic information
Product Name:3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid
Synonyms:3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid;3-(Acetylhydroxyamino)propylphosphonic acid;3-Phosphono 1-(N-acetylhydroxyamino)propane;Phosphonic acid, P-[3-(acetylhydroxyamino)propyl]-
CAS:66508-32-5
MF:C5H12NO5P
MW:197.13
EINECS:
Product Categories:
Mol File:66508-32-5.mol
3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid Structure
3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid Chemical Properties
Boiling point 448.9±55.0 °C(Predicted)
density 1.492±0.06 g/cm3(Predicted)
pka2.42±0.10(Predicted)
Safety Information
MSDS Information
3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid Usage And Synthesis
UsesFR900098 is an antimalarial agent that inhibits 1-deoxy-d-xylulose-5-phosphate (DXP) reductoisomerase. FR900098 has no significant acute toxicity or genotoxicity, and does not have the ability to cause chromosome breakage or heterogeneity. FR900098 has no effect on bone marrow red blood cells in NMRI mice[1].
DefinitionChEBI: FR 900098 is a phosphonoacetic acid.
References[1] Wiesner J, et al. FR-900098, an antimalarial development candidate that inhibits the non-mevalonate isoprenoid biosynthesis pathway, shows no evidence of acute toxicity and genotoxicity. Virulence. 2016 Aug 17;7(6):718-28. DOI:10.1080/21505594.2016.1195537
3-(N-acetyl-N-hydroxy)aminopropylphosphonic acid Preparation Products And Raw materials
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