| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Aspergillomarasmine A
CAS:3484-65-9
Package:25mg/RMB 17200
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| Company Name: |
Xinyi Yufeng Chemical Co., LTD
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| Tel: |
516-18921756018 18921756018 |
| Email: |
864733450@QQ.COM |
| Products Intro: |
Product Name:Aspergillomarasmine A
CAS:3484-65-9
Purity:95% Package:25mg;50mg;100mg
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| | aspergillomarasmine A Basic information |
| Product Name: | aspergillomarasmine A | | Synonyms: | aspergillomarasmine A;L-Aspartic acid, N-[(2S)-2-[[(2S)-2-amino-2-carboxyethyl]amino]-2-carboxyethyl]-;Toxin C (Pyrenophora teres) | | CAS: | 3484-65-9 | | MF: | C10H17N3O8 | | MW: | 307.26 | | EINECS: | | | Product Categories: | | | Mol File: | 3484-65-9.mol |  |
| | aspergillomarasmine A Chemical Properties |
| Boiling point | 637.6±55.0 °C(Predicted) | | density | 1.579±0.06 g/cm3(Predicted) | | pka | 2.12±0.23(Predicted) |
| | aspergillomarasmine A Usage And Synthesis |
| Uses | Aspergillomarasmine A is a natural aminopolycarboxylic acid with potent inhibitory activity against class B metallo-β-lactamases (MBLs). Aspergillomarasmine A inactivates MBLs by removing a catalytic Zn2+ cofactor. Aspergillomarasmine A acts as a selective Zn2+ scavenger, promoting the dissociation of the metal cofactor, thereby indirectly inactivating NDM-1. Aspergillomarasmine A causes the loss of Zn2+ ions from the low-affinity binding site of NDM-1. The action of Aspergillomarasmine A results in the rapid degradation of Zn2+-deficient NDM-1, thereby enhancing its potency as a β-lactam enhancer. The mechanism of Aspergillomarasmine A has broad applicability among different Zn2+ chelators[1]. | | Definition | ChEBI: Aspergillomarasmine A is an aspartic acid derivative. | | References | [1] Aspergillomarasmine A inhibits metallo-β-lactamases by selectively sequestering Zn2 |
| | aspergillomarasmine A Preparation Products And Raw materials |
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