SRD5A1-IN-1 manufacturers
- SRD5A1-IN-1
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- $58.00
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2026-07-14
- CAS:2279077-93-7
- Purity: 99.77%
- Supply Ability: 10g
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| | SRD5A1-IN-1 Basic information |
| Product Name: | SRD5A1-IN-1 | | Synonyms: | 2-Propenamide, N-[3,5-bis(trifluoromethyl)phenyl]-3-(3,4-dihydroxyphenyl)-, (2E)-;SRD5A1-IN-1, 10 mM in DMSO;(E)-N-(3,5-Bis(trifluoromethyl)phenyl)-3-(3,4-dihydroxyphenyl)acrylamide | | CAS: | 2279077-93-7 | | MF: | C17H11F6NO3 | | MW: | 391.27 | | EINECS: | | | Product Categories: | | | Mol File: | 2279077-93-7.mol |  |
| | SRD5A1-IN-1 Chemical Properties |
| Boiling point | 486.575±45.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.533±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 9.343±0.10(predicted) | | form | Solid | | color | White to off-white |
| | SRD5A1-IN-1 Usage And Synthesis |
| Uses | SRD5A1-IN-1 (Compound 4) is a competitive and covalent steroid 5α-reductase type 1 (SRD5A1) inhibitor with an IC50 of 1.44 μM. SRD5A1-IN-1 modulates SRD5A1 function, leading to a lower level of dihydrotestosterone (DHT) production and SRD5A1 protein suppression[1]. | | References | [1] Lin A C K, et al. Caffeic acid N-[3, 5-bis (trifluoromethyl) phenyl] amide as a non-steroidal inhibitor for steroid 5α-reductase type 1 using a human keratinocyte cell-based assay and molecular dynamics. Scientific Reports, 2022, 12(1): 1-20. |
| | SRD5A1-IN-1 Preparation Products And Raw materials |
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