Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester

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Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester Basic information
Product Name:Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester
Synonyms:Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester;Diphosphatidylglycerol (16:0);Cardiolipin (16:0/16:0/16:0/16:0);Hexadecanoic acid, (2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diphosphapentadecane-1,2,14,15-tetrayl ester
CAS:105380-95-8
MF:C73H142O17P2
MW:1353.85
EINECS:
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Mol File:105380-95-8.mol
Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester Structure
Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester Chemical Properties
Boiling point 1091.866±75.00 °C(Press: 760.00 Torr)(predicted)
density 1.030±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
solubility Chloroform: Soluble
pka0.999±0.50(predicted)
Safety Information
MSDS Information
Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester Usage And Synthesis
Uses16:0 Cardiolipin (Diphosphatidylglycerol (16:0)) is a phospholipid derived from Palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads[1].
References[1] Junxiang Zhou, et al. A feedback loop engaging propionate catabolism intermediates controls mitochondrial morphology. Nat Cell Biol. 2022 Apr;24(4):526-537. DOI:10.1038/s41556-022-00883-2
[2] MARIANA FERREIRA. Fluoroquinolone Metalloantibiotics: Fighting Staphylococcus aureus Biofilms[J]. Micro & Nano Letters, 2022, 187 1. DOI: 10.3390/micro2030027
[3] HANA KIM  Gi Y L  Young Do Yoo. Identification of Bacterial Membrane Selectivity of Romo1-Derived Antimicrobial Peptide AMPR-22 via Molecular Dynamics.[J]. International Journal of Molecular Sciences, 2022, 23 13. DOI: 10.3390/ijms23137404
Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester Preparation Products And Raw materials
Tag:Hexadecanoic acid (R)-2-({3-[((R)-2,3-bis-hexadecanoyloxy-propoxy)-hydroxy-phosphoryloxy]-2-hydroxy-propoxy}-hydroxy-phosphoryloxy)-1-hexadecanoyloxymethyl-ethyl ester(105380-95-8) Related Product Information
1',3'-bis[1,2-dioleoyl-sn-glycero-3-phospho]-sn-glycerol (sodiuM salt) 9-Octadecenoic acid (9Z)-, 1,1'-[(1R,13R)-4,7,10-trihydroxy-4,10-dioxido-1,13-bis[[(1-oxohexadecyl)oxy]methyl]-3,5,9,11-tetraoxa-4,10-diphosphatridecane-1,13-diyl] ester, sodium salt (1:2) 1',3'-bis[1,2-diMyristoyl-sn-glycero-3-phospho]-sn-glycerol (sodiuM salt) Cardiolipin (CL), (sodiuM or aMMoniuM salt) (bovine) Octadecanoic acid, 5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diphosphapentadecane-1,2,14,15-tetrayl ester, disodium salt, [R-(R*,R*)]- (9CI) DSPE-PEG-Mal