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| | SJ995973 Basic information |
| Product Name: | SJ995973 | | Synonyms: | SJ995973;2-((S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(5-(2-(4-(2,6-dioxopiperidin-3-yl)phenoxy)acetamido)pentyl)acetamide;6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[5-[[2-[4-(2,6-dioxo-3-piperidinyl)phenoxy]acetyl]amino]pentyl]-2,3,9-trimethyl-, (6S)-;(6S)-4-(4-Chlorophenyl)-N-[5-[[2-[4-(2,6-dioxo-3-piperidinyl)phenoxy]acetyl]amino]pentyl]-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide | | CAS: | 2882065-25-8 | | MF: | C37H40ClN7O5S | | MW: | 730.28 | | EINECS: | | | Product Categories: | | | Mol File: | 2882065-25-8.mol |  |
| | SJ995973 Chemical Properties |
| density | 1.428±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 11.357±0.40(predicted) | | form | Solid | | color | Off-white to light yellow |
| | SJ995973 Usage And Synthesis |
| Uses | SJ995973 (PROTAC) is a uniquely potent degrader of bromodomain and extra-terminal (BET) proteins. | | References | [1] Min J, et al. Phenyl-Glutarimides: Alternative Cereblon Binders for the Design of PROTACs. Angew Chem Int Ed Engl. 2021 Dec 13;60(51):26663-26670. DOI:10.1002/anie.202108848 |
| | SJ995973 Preparation Products And Raw materials |
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