| Company Name: |
AnalyticsStanza Inc
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| Tel: |
+91-7032031309 |
| Email: |
info@analyticsstanza.com |
| Products Intro: |
Product Name:Tenivastatincalcium Salt impurity (OR) Simvastatin impurity A
CAS:121009-77-6
Purity:98.10 Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
Shenzhen SUNGENING Bio-Medical Co., Ltd.
|
| Tel: |
0755-28967200 13631290199 |
| Email: |
wxf@sungening.com |
| Products Intro: |
Product Name:Simvastatin Impurity 1
CAS:121009-77-6
Purity:99% HPLC or More Package:10MG;25MG;50MG;100MG
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simvastatin acid manufacturers
- Tenivastatin
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- $786.00 / 5mg
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2026-04-16
- CAS:121009-77-6
- Min. Order:
- Purity: 99.56%
- Supply Ability: 10g
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| | simvastatin acid Basic information |
| Product Name: | simvastatin acid | | Synonyms: | (3R,5R)-3,5-Dihydroxy-7-[(1S)-1-(2,2-dimethylbutyryloxy)-3β,7α-dimethyl-1,2,3,7,8,8aα-hexahydronaphthalene-8α-yl]heptanoic acid;(βR,δR,1S)-8α-(2,2-Dimethyl-1-oxobutoxy)-1,2,6,7,8,8aβ-hexahydro-β,δ-dihydroxy-2β,6α-dimethyl-1β-naphthaleneheptanoic acid;2,2-Dimethylbutanoic acid [(1S)-1,2,3,7,8,8aα-hexahydro-3β,7α-dimethyl-8α-[(3R,5R)-3,5-dihydroxy-6-carboxyhexyl]naphthalen]-1β-yl ester;2,2-Dimethylbutyric acid (1S)-3β,7α-dimethyl-8α-[(3R,5R)-3,5-dihydroxy-6-carboxyhexyl]-1,2,3,7,8,8aα-hexahydronaphthalene-1β-yl ester;Simvastatin hydroxy acid;(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid;1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-β,δ-dihydroxy-2,6-dimethyl-, (βR,δR,1S,2S,6R,8S,8aR)-;Tenivastatin | | CAS: | 121009-77-6 | | MF: | C25H40O6 | | MW: | 436.585 | | EINECS: | | | Product Categories: | | | Mol File: | 121009-77-6.mol |  |
| | simvastatin acid Chemical Properties |
| Boiling point | 607.0±55.0 °C(Predicted) | | density | 1.13±0.1 g/cm3(Predicted) | | pka | 4.31±0.10(Predicted) | | EPA Substance Registry System | 1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-?,?-dihydroxy-2,6-dimethyl-, (?R,?R,1S,2S,6R,8S,8aR)- (121009-77-6) |
| | simvastatin acid Usage And Synthesis |
| Uses | Simvastatin acid (Tenivastatin), a hydrolysate of Simvastatin (HY-17502), is a HMG-CoA reductase (HMGCR) inhibitor. Simvastatin acid reduces Indoxyl sulfate-mediated reactive oxygen species (ROS) production in human cardiomyocytes. Simvastatin acid can also modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene[1][2]. | | Definition | ChEBI: Simvastatin hydroxy acid is a carbonyl compound. | | References | [1] Eduardo Filipe Oliveira, et al. HMG-CoA Reductase inhibitors: an updated review of patents of novel compounds and formulations (2011-2015). Expert Opin Ther Pat. 2016 Nov;26(11):1257-1272. DOI:10.1080/13543776.2016.1216977
[2] Atilano-Roque A, et al. Characterization of simvastatin acid uptake by organic anion transporting polypeptide 3A1 (OATP3A1) and influence of drug-drug interaction. Toxicol In Vitro. 2017 Dec;45(Pt 1):158-165. DOI:10.1016/j.tiv.2017.09.002 |
| | simvastatin acid Preparation Products And Raw materials |
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