PD-1/PD-L1-IN-34 manufacturers
- PD-1/PD-L1-IN-34
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- $1370.00
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2026-05-11
- CAS:2924403-17-6
- Purity:
- Supply Ability: 10g
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| | PD-1/PD-L1-IN-34 Basic information |
| Product Name: | PD-1/PD-L1-IN-34 | | Synonyms: | PD-1/PD-L1-IN-34;L-Alanine, N-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[(1S,2S)-2-(2-methyl[1,1′-biphenyl]-3-yl)cyclopropyl]phenyl]methyl]-2-methyl- | | CAS: | 2924403-17-6 | | MF: | C35H33ClN2O3 | | MW: | 565.1 | | EINECS: | | | Product Categories: | | | Mol File: | 2924403-17-6.mol |  |
| | PD-1/PD-L1-IN-34 Chemical Properties |
| Boiling point | 706.686±60.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.286±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 2.056±0.10(predicted) |
| | PD-1/PD-L1-IN-34 Usage And Synthesis |
| Uses | PD-1/PD-L1-IN-34 (Compound (1S,2S)-A25) inhibits PD-1/PD-L1 interaction (IC50=0.029 μM), with a selected binding affinity with PD-L1 (KD=0.1554 μM). PD-1/PD-L1-IN-34 inhibits tumor growth by activating the immune microenvironment[1]. | | References | [1] Jing T, et al. Discovery and Optimization of Novel Biphenyl Derivatives Bearing Cyclopropyl Linkage as Potent Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Inhibitors. J Med Chem. 2023 May 25;66(10):6811-6835. DOI:10.1021/acs.jmedchem.3c00205 |
| | PD-1/PD-L1-IN-34 Preparation Products And Raw materials |
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