Pim-1 kinase inhibitor 10

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Pim-1 kinase inhibitor 10 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Pim-1 kinase inhibitor 10 Basic information
Product Name:Pim-1 kinase inhibitor 10
Synonyms:Pim-1 kinase inhibitor 10;3-Pyridinecarbonitrile, 4-(1,2-dihydro-2-oxo-3-quinolinyl)-1,2-dihydro-6-(3-hydroxyphenyl)-2-oxo-
CAS:2918764-57-3
MF:C21H13N3O3
MW:355.35
EINECS:
Product Categories:
Mol File:2918764-57-3.mol
Pim-1 kinase inhibitor 10 Structure
Pim-1 kinase inhibitor 10 Chemical Properties
Boiling point 656.538±55.00 °C(Press: 760.00 Torr)(predicted)
density 1.492±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka7.282±0.10(predicted)
Safety Information
MSDS Information
Pim-1 kinase inhibitor 10 Usage And Synthesis
UsesPim-1 kinase inhibitor 10 (compound 13a) is a both competitive and non-competitive inhibitor of PIM-1/2 kinase. Pim-1 kinase inhibitor 10 can induce cell apoptosis and exhibits anticancer activity. Pim-1 kinase inhibitor 10 also induces caspase 3/7 activation[1].
References[1] El-Miligy MMM, et, al. Discovery of new pyridine-quinoline hybrids as competitive and non-competitive PIM-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2152810. DOI:10.1080/14756366.2022.2152810
Pim-1 kinase inhibitor 10 Preparation Products And Raw materials
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