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| | (-)-5-HT2C agonist-3 Basic information |
| Product Name: | (-)-5-HT2C agonist-3 | | Synonyms: | (-)-5-HT2C agonist-3;Benzenemethanamine, N-[[(1R,2R)-2-(5-fluoro-2-methoxyphenyl)cyclopropyl]methyl]-2-methoxy-, hydrochloride (1:1) | | CAS: | 2104810-16-2 | | MF: | C19H22FNO2.ClH | | MW: | 351.84 | | EINECS: | | | Product Categories: | | | Mol File: | 2104810-16-2.mol |  |
| | (-)-5-HT2C agonist-3 Chemical Properties |
| | (-)-5-HT2C agonist-3 Usage And Synthesis |
| Uses | (-)-5-HT2C agonist-3 (compound (–)-19) is a 5-HT2C selective agonist with Gq signaling preference, with EC50 values for 5-HT2 receptors of 5-HT2C: 103 nM; 5-HT2B: 570 nM; 5-HT2A: 72 nM. (-)-5-HT2C agonist-3 can be used in antipsychotic research[1]. | | IC 50 | 5-HT2A Receptor: 72 nM (IC50); 5-HT2C Receptor: 103 nM (IC50); 5-HT2B Receptor: 570 nM (IC50) | | References | [1] Guiping Zhang, et al. "Discovery of N-substituted (2-phenylcyclopropyl) methylamines as functionally selective serotonin 2C receptor agonists for potential use as antipsychotic medications." Journal of medicinal chemistry 60.14 (2017): 6273-6288. |
| | (-)-5-HT2C agonist-3 Preparation Products And Raw materials |
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