PAN-MUTATION KRAS PROTAC 基本信息
| 中文名称 | PAN-MUTATION KRAS PROTAC |
|---|---|
| 中文同义词 | (2S,4R)-1-((R)-2-(3-(4-((S)-4-(4-(5-((S)-2-氨基-3-氰基-4-甲基-4,5,6,7-四氢苯并噻吩-4-基)-1,2,4-恶二唑-3-基)嘧啶-2-基)-3-甲基-1,4-二氮杂-1-基)丁氧基)异恶唑-5-基)-3-甲基丁酰基)-4-羟基-N-(4-(4-甲基噻唑-5-基)苄基)吡咯烷-2-甲酰胺;(2S,4R)-1-((R)-2-(3-(4-((S)-4-(4-(5-((S)-2-氨基-3-氰基-4-甲基-4,5,6,7-四氢苯并[b]噻吩-4-基)-1,2,4-恶二唑-3-基)嘧啶-2-基)-3-甲基-1,4-二氮杂环庚烷-1-基)丁氧基)异恶唑-5-基)-3-甲基丁酰基)-4-羟基-N-(4-(4-甲基噻唑-5-基)苄基)吡咯烷-2-甲酰胺;PROTAC K-Ras Degrader-4试剂;PROTAC K-Ras Degrader-4试剂;(2S,4R)-1-((R)-2-(3-(4-((S)-4-(4-(5-((S)-2-氨基-3-氰基-4-甲基-4,5,6,7-四氢苯并[b]噻吩-4-基)-1,2,4-恶二唑-3-基)嘧啶-2-基)-3-甲基-1,4-二氮杂环庚烷-1-基)丁氧基)异恶唑-5-基)-3-甲基丁酰基)-4-羟基-N-(4-(4-甲基噻唑;化合物 PROTAC K-Ras Degrader-4 |
| 英文名称 | 2938169-99-2 |
| 英文同义词 | CB514909530;Pan-Mutation KRAS PROTAC;PROTAC K-Ras Degrader-4;2-Pyrrolidinecarboxamide, 1-[(2R)-2-[3-[4-[(3S)-4-[4-[5-[(4S)-2-amino-3-cyano-4,5,6,7-tetrahydro-4-methylbenzo[b]thien-4-yl]-1,2,4-oxadiazol-3-yl]-2-pyrimidinyl]hexahydro-3-methyl-1H-1,4-diazepin-1-yl]butoxy]-5-isoxazolyl]-3-methyl-1-oxobutyl]-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (2S,4R)-;(2S,4R)-1-((R)-2-(3-(4-((S)-4-(4-(5-((S)-2-Amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-4-yl)-1,2,4-oxadiazol-3-yl)pyrimidin-2-yl)-3-methyl-1,4-diazepan-1-yl)butoxy)isoxazol-5-yl)-3-methylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide;(2S,4R)-1-((R)-2-(3-(4-((S)-4-(4-(5-((S)-2-Amino-3-cyano-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophen-4-yl)-1,2,4-oxadiazol-3-yl)pyrimidin-2-yl)-3-methyl-1,4-diazepan-1-yl)butoxy)isoxazol-5-yl)-3-methy |
| CAS号 | 2938169-99-2 |
| 分子式 | C50H60N12O6S2 |
| 分子量 | 989.22 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 2938169-99-2.mol |
| 结构式 |  |
PAN-MUTATION KRAS PROTAC 性质
| 密度 | 1.412±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
|---|---|
| 形态 | Solid |
| 酸度系数(pKa) | 14.059±0.40(predicted) |
| 颜色 | White to light yellow |