(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate

(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate Suppliers list

Company Name:	3B Pharmachem (Wuhan) International Co.,Ltd.
Tel:	18930552037
Email:	3bsc@sina.com

Company Name:	Ascent Scientific
Tel:	4401179829988
Email:	customerservice@ascentscientific.co.uk

Company Name:	Energy Chemical
Tel:	021-58432009 400-005-6266
Email:	marketing@energy-chemical.com

(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate Basic information

Product Name:	(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate
Synonyms:	(1r)-ethanon;anatoxini;(+/-)-ANATOXIN A;(+/-)-ANATOXIN A FUMARATE;(+/-)-ANATOXIN A FUMERATE;(-)-Anatoxin;(1β,6β)-5-Acetyl-9-azabicyclo[4.2.1]non-4-ene;[1S,6S,(-)]-2-Acetyl-9-azabicyclo[4.2.1]non-2-ene
CAS:	64285-06-9
MF:	C10H15NO
MW:	165.23
EINECS:
Product Categories:	Nicotinic;Acetylcholine receptor;Pharmaceuticals;Intermediates & Fine Chemicals;Amines
Mol File:	64285-06-9.mol

(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate Chemical Properties

alpha	D25 +39.8°
Boiling point	293.09°C (rough estimate)
density	1.0203 (rough estimate)
refractive index	1.5200 (estimate)
storage temp.	Desiccate at +4°C
pka	9.4(at 25℃)
form	White solid.
color	Oil
Henry's Law Constant	1.5×10³ mol/(m³Pa) at 25℃, HSDB (2015)
EPA Substance Registry System	Ethanone, 1-(1R,6R)-9-azabicyclo[4.2.1]non-2-en-2-yl- (64285-06-9)

Safety Information

Hazardous Substances Data	64285-06-9(Hazardous Substances Data)
Toxicity	LD50 i.p. in mice: 200 mg/kg (Carmichael)

MSDS Information

(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate Usage And Synthesis

Acute toxicity	Intraperitoneal-mouse LDL0: 0.25 mg/kg
Occurrence	An oily alkaloid, anatoxin-a has been isolated from Anabaena jfos-aquae.
Uses	(+)-Anatoxin-a is a secondary, bicyclic amine alkaloid and cyanotoxin with acute neurotoxicity. The toxin is produced by at least four different genera of cyanobacteria and has been reported in North America, Europe, Africa, Asia, and New Zealand. Symptoms of anatoxin exposure are loss of coordination, muscular fasciculations, convulsions and death by respiratory paralysis.
Synthesis Reference(s)	Journal of the American Chemical Society, 106, p. 4539, 1984 DOI: 10.1021/ja00328a040
Biological Activity	A potent nicotinic agonist (K i values are 1.25 and 1840 nM for α 4 β 2 and α 7 nicotinic receptors respectively). Stimulates [ 3 H]-dopamine release from rat striatal synaptosomes (EC 50 = 136 nM).
Safety Profile	Poison by intraperitoneal route.An experimental teratogen. When heated todecomposition it emits toxic fumes of NOx.

(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate Preparation Products And Raw materials

Tag:(+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate(64285-06-9) Related Product Information

Herba Houttuyniae Polysaccharide (+)-Anatoxin a hydrochloride (+/-)-2-Acetyl-9-aza bicyclo[4.2.1]non-2-ene fumarate Nodular toxin MICROCYSTIN-LR

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