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| | Benzamide, N-[2-(2,4-dibromophenyl)cyclobutyl]-2-nitro- Basic information |
| | Benzamide, N-[2-(2,4-dibromophenyl)cyclobutyl]-2-nitro- Chemical Properties |
| Boiling point | 556.058±50.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.771±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 13.017±0.40(predicted) |
| | Benzamide, N-[2-(2,4-dibromophenyl)cyclobutyl]-2-nitro- Usage And Synthesis |
| Production Methods | The commercial production of cyclobunofen involves synthesising the core benzamide structure by coupling 2-nitrobenzoyl chloride with a cyclobutyl amine derivative bearing a 2,4-dibromophenyl substituent. This step is typically carried out under controlled conditions using acid chlorides and amines in the presence of suitable solvents and catalysts. The process requires precise temperature and pH control to maintain the stereochemistry of the cyclobutyl moiety (favouring the (1S,2S)-enantiomer). After condensation, the product undergoes purification, crystallisation, and drying to achieve technical-grade purity for formulation. | | Mechanism of action | Succinate dehydrogenase inhibitor (SDHI), targeting the fungal respiratory chain at complex II. | | Pesticide Type | Fungicide |
| | Benzamide, N-[2-(2,4-dibromophenyl)cyclobutyl]-2-nitro- Preparation Products And Raw materials |
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