BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT

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BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Basic information
Product Name:BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT
Synonyms:8-bromo-?phenyl-1,n?ethenoguanosine-3’,5’-cyclicmonophosphorothioate,sp-isomer(sp-8-br-pet-cg;8-bromo-beta-phenyl-1,n(2)-ethenoguanosine3’,5’-cyclicmonophosphorothioate;SP-8-BR-PET-CGMPS, NA;SP-8-BR-PET-CGMPS SODIUM SALT;GUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE, BETA-PHENYL-1,N2-ETHENO-8-BROMO-, SP-ISOMER, SODIUM SALT;BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT;Sp-8-Br-PET-cGMPS
CAS:172806-21-2
MF:C18H16BrN5NaO6PS
MW:564.28
EINECS:
Product Categories:
Mol File:172806-21-2.mol
BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Structure
BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Chemical Properties
Safety Information
MSDS Information
BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Usage And Synthesis
UsesSp-8-Br-PET-cGMPS is a membrane-permeable PKG agonist and a membrane-permeable inhibitor of retinal-type cGMP-gated ion channels, as well as an activator of cGMP-dependent protein kinases I α and I β. Sp-8-Br-PET-cGMPS is resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, has no metabolic side effects, and is more lipophilic and permeable than Sp-8-pCPT-cGMPS. Sp-8-Br-PET-cGMPS can be used to study the role of cGMP signaling pathways in the nervous system[1].
References[1] Barnstable, Colin J., Ji-Ye Wei, et al. Modulation of synaptic function by cGMP and cGMP-gated cation channels. Neurochemistry international 45.6 (2004): 875-884. DOI:10.1016/j.neuint.2004.03.018
BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT Preparation Products And Raw materials
Tag:BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT(172806-21-2) Related Product Information
8-Bromoguanosine BETA-PHENYL-1,N2-ETHENO-8-BROMOGUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT sodium O,O-dimethyl thiophosphate Imidazole-2-carboxaldehyde SODIUM O,O-DIETHYLTHIOPHOSPHATE 1-NH2-CGMP SODIUM SALT