N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide

N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Suppliers list
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N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Basic information
Product Name:N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
Synonyms:Rosuvastatin (5S)-Lactone/N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonam;Rosuvastatin Impurity 1/Rosuvastatin EP Impurity D/Rosuvastatin (3R,5S)-Lactone;Rosuvastatin calcium-5;Rosuvastatin EP Imp D;Rosuvastatin Impurity 6(Rosuvastatin EP Impurity D);Rosuvastatin Lactone EP impurity D;Rosuvastatin Calcium EP Impurity D;N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
CAS:503610-43-3
MF:C22H26FN3O5S
MW:463.52
EINECS:
Product Categories:Aromatics;Chiral Reagents;Intermediates & Fine Chemicals;Isotopically Labeled Pharmaceutical Reference Standard;Pharmaceuticals;Sulfur & Selenium Compounds
Mol File:503610-43-3.mol
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Structure
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Chemical Properties
Melting point 131 °C
Boiling point 695.0±65.0 °C(Predicted)
density 1.387
storage temp. -20°C Freezer
solubility Chloroform (Slightly), Methanol (Slightly)
pka13.22±0.40(Predicted)
form Solid
color White to Off-White
Major Applicationpharmaceutical
InChIKeySOEGVMSNJOCVHT-VEUZHWNKSA-N
SMILESFc1ccc(cc1)c2nc(nc(c2\C=C\[C@H]3OC(=O)C[C@@H](C3)O)C(C)C)N([S](=O)(=O)C)C
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
Hazard ClassificationsSTOT RE 2 Oral
MSDS Information
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Usage And Synthesis
Chemical PropertiesWhite Solid
UsesAn isomer of Rosuvastatin Lactone (R700500); intermediate in the production of Rosuvastatin (R700500) derivatives.
UsesRosuvastatin Lactone (Rosuvastatin EP Impurity D) is an intermediate in the production of Rosuvastatin (R700500) derivatives.
DefinitionChEBI: Rosuvastatin lactone is a member of pyrimidines.
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide Preparation Products And Raw materials
Tag:N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide(503610-43-3) Related Product Information
Rosuvastatin EP Impurity E (Calcium Salt) Pitavastatin Impurity 8 Rosuvastatin Impurity 14 (3R,5R)-Rosuvastatin (3S,5R)-Rosuvastatin Methyl Ester Rosuvastatin IMpurity (5-Oxo Rosuvastatin tert-Butyl Ester) Rosuvastatin Anhydro Lactone Rosuvastatin IsoaMy Ester Rosuvastatin EP impurity A (3S,5R)-Rosuvastatin Rosuvastatin methyl ester tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate 4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol 3-Oxo Rosuvastatin SodiuM Salt Rosuvastatin ethyl ester Rosuvastatin EP impurity H Rosuvastatin N-Desmethyl rosuvastatin-d3