Egrifta manufacturers
- Tesamorelin
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- $1.00
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2026-09-12
- CAS:
- Min. Order: 1kit
- Purity: 99.9%
- Supply Ability: 200
- Tesamorelin
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2025-08-22
- CAS:804475-66-9
- Min. Order: 1GRAM
- Purity: 99%
- Supply Ability: 20 TONS
- Tesamorelin
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- $100.00
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2025-04-16
- CAS:804475-66-9
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100kg
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| | Egrifta Basic information |
| Product Name: | Egrifta | | Synonyms: | Th 9507;Th-9507;Unii-mqg94m5eeo;High Pure Peptides Th9507 Tesamorelin Powder 2mg/Vial;Egrifta;Tesamerelin | | CAS: | 804475-66-9 | | MF: | C221H366N72O67S | | MW: | 5135.77794 | | EINECS: | 200-048-4 | | Product Categories: | | | Mol File: | 804475-66-9.mol |  |
| | Egrifta Chemical Properties |
| InChIKey | QBEPNUQJQWDYKU-BMGKTWPMSA-N |
| | Egrifta Usage And Synthesis |
| Description | Tesamorelin acetate is an analog of growth hormone-releasing hormone
(GHRH) that was approved in the United States in 2010 for treatment of
lipodystrophy in HIV patients.
Tesomorelin is an analog of GHRH. GHRH stimulates the synthesis
and release of GH. In the pituitary, GH is secreted in a pulsatile manner.
GH control is regulated by somatostatin and the negative feedback regulator,
IGF-1. Direct administration of GH to patients with lipodystrophy
decreases VAT but has associated side effects such as fluid retention and
joint swelling. Because of the side effects associated with direct GH
administration, GHRH represents a attractive mechanism for increasing
GH levels. Tesomorelin is an analog of GHRH in which the N-terminal
amino acid, Tyr, is amidated with a trans-3-hexenoyl group. Capping of
the N-terminus protects GHRH from cleavage by DPP-4. Tesomorelin
demonstrates enhanced stability compared with GHRH in animal models. | | Originator | Theratechnologies (Canada) | | Uses | Egrifta (Tesamorelin) is used to reduce excess abdominal fat in HIV-infected lipodystrophy patients. Some HIV medicines cause this side effect (increased fat in the upper back and abdomen and decreased fat in the arms and legs.) Tesamorelin works by making the body produce more growth hormone. This medicine should not be used for weight loss. | | Brand name | Egrifta | | Biological Activity | Egrifta (Tesamorelin) is a synthetic growth hormone-releasing hormone analog and a GHRH agonist that stimulates the synthesis and release of endogenous growth hormone. | | Side effects | Adverse reactions to Egrifta (Tesamorelin) include redness, itching, pain, irritation, or bruising at the injection site. Muscle soreness may also occur. In addition, muscle/joint pain or stiffness; numbness/tingling/swelling in the arms or legs; elevated blood sugar (increased thirst/urination), Rare adverse reactions include: very severe allergic reactions such as rash, itching/swelling (especially of the face/tongue/throat), dizziness, facial severity, difficulty breathing; and an increased risk of new cancers or recurrence of previous melanoma. |
| | Egrifta Preparation Products And Raw materials |
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