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1-631-485-4226; 16314854226 |
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info@bocsci.com |
| Company Name: |
SIMAGCHEM CORP |
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Managlinat dialanetil manufacturers
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| | Managlinat dialanetil Basic information |
| Product Name: | Managlinat dialanetil | | Synonyms: | Managlinat dialanetil;Managlinat Dialanetil/CS-917;MB 06322;L-Alanine, N,N'-[[5-[2-amino-5-(2-methylpropyl)-4-thiazolyl]-2-furanyl]phosphinylidene]bis-, 1,1'-diethyl ester;MB06322 (CS-917);CS-917;diethyl 2,2'-(((5-(2-amino-5-isobutylthiazol-4-yl)furan-2-yl)phosphoryl)bis(azanediyl))(2S,2'S)-dipropionate | | CAS: | 280782-97-0 | | MF: | C21H33N4O6PS | | MW: | 500.55 | | EINECS: | | | Product Categories: | Other APIs | | Mol File: | 280782-97-0.mol |  |
| | Managlinat dialanetil Chemical Properties |
| Boiling point | 634.8±65.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | pka | 4.13±0.10(Predicted) | | form | Solid | | color | White to yellow |
| | Managlinat dialanetil Usage And Synthesis |
| Uses | Managlinat dialanetil (MB06322) is an orally bioavailable inhibitor of fructose 1,6-bisphosphatase (FBPase) for the treatment of type 2 diabetes[1] [2]. | | in vivo | Managlinat dialanetil dose-dependently inhibits GNG as well as lower basal and postprandial blood glucose levels in Zucker diabetic fatty (ZDF) rats after oral administration[1].
| | References | [1] Wang Y, et al. Managlinat dialanetil, a fructose-1,6-bisphosphatase inhibitor for the treatment of type 2 diabetes. Curr Opin Investig Drugs. 2007 Oct;8(10):849-58. PMID:17907062 |
| | Managlinat dialanetil Preparation Products And Raw materials |
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