2-oxa-6-azaspiro[3.4]octane

2-oxa-6-azaspiro[3.4]octane Suppliers list

Company Name:	Shanghai Benso Pharmaceutical Technology Co., Ltd. Gold
Tel:	15088289376;13917786310
Email:	248775804@qq.com

Company Name:	nanjing dingda Pharmatech. co. ltd Gold
Tel:	18013843276
Email:	1642441764@qq.com

Company Name:	JinYan Chemicals(ShangHai) Co.,Ltd.
Tel:	13817811078
Email:	sales@jingyan-chemical.com

Company Name:	Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel:	13761987713
Email:	hxzheng@sunwaypharm.cn

2-oxa-6-azaspiro[3.4]octane manufacturers

2-oxa-6-azaspiro[3.4]octane Basic information

Product Name:	2-oxa-6-azaspiro[3.4]octane
Synonyms:	2-oxa-6-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octa...;2-oxa-6-azaspiro[3.4]octane, hemioxalate salt;2-oxa-7-azaspiro[3.4]octane;2-Oxa-6-azaspiro[3.4]octane,95%;2-Oxa-6-azaspiro[3.4]octane (9CI, ACI);2-Oxa-6-azaspiro[3.4]octane 96%min
CAS:	220290-68-6
MF:	C6H11NO
MW:	113.16
EINECS:
Product Categories:
Mol File:	220290-68-6.mol

2-oxa-6-azaspiro[3.4]octane Chemical Properties

Boiling point	187℃
density	1.08
Fp	63°(145°F)
storage temp.	2-8°C(protect from light)
pka	10.55±0.20(Predicted)
Appearance	Light yellow to yellow Liquid
Water Solubility	Soluble in water.
InChI	InChI=1S/C6H11NO/c1-2-7-3-6(1)4-8-5-6/h7H,1-5H2
InChIKey	ZHAIMJRKJKQNQI-UHFFFAOYSA-N
SMILES	C1C2(CCNC2)CO1

Safety Information

HS Code

29339900

MSDS Information

2-oxa-6-azaspiro[3.4]octane Usage And Synthesis

Uses	2-Oxa-6-azaspiro[3.4]octane is involved in the preparation of azaspirocycle or azetidine substituted 4-anilinoquinazoline derivatives, which exhibits epidermal growth factor receptor (EGFR) inhibitory activities.
Application	2-Oxa-6-Azaspiro[3.4]Octane Hydrochloride may be useful in the preparation of aminocyanopyridine derivatives for the prevention or treatment of cancer or inflammatory diseases.
Synthesis	Tert-butyl 2-oxa-6-azaspiro[3.4]octane-6-carboxylate (86mg, 0.4mmol) was dissolved in dichloromethane (1mL), trifluoroacetic acid (2mL) was added to the system at room temperature, and the reaction solution was heated at 60°C for 2h. The reaction solution was cooled to room temperature and concentrated under reduced pressure to obtain crude product 2-oxa-6-azaspiro[3.4]octane.

2-oxa-6-azaspiro[3.4]octane Preparation Products And Raw materials

Tag:2-oxa-6-azaspiro[3.4]octane(220290-68-6) Related Product Information

2-Oxa-6-azaspiro[3.4]octan-7-one 2-oxa-6-azaspiro[3,4]octane-6-carboxylic acid tert-butyl ester 1-Oxa-6-azaspiro[3.3]heptane oxalate [3-(methoxymethyl)pyrrolidin-3-yl]methanol 3-(methoxymethyl)-3-methylpyrrolidine ethyl[(oxolan-3-yl)methyl]amine