3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE

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Company Name: TargetMol Chemicals Inc.  
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3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE Basic information
Product Name:3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE
Synonyms:BRL 54443 MALEATE;3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE;3-(1-Methylpiperidin-4-yl)-1H-indol-5-ol maleate salt;BRL 54443 maleate salt;1H-Indol-5-ol, 3-(1-methyl-4-piperidinyl)-, (2Z)-2-butenedioate (1:1)
CAS:1197333-54-2
MF:C18H22N2O5
MW:346.38
EINECS:
Product Categories:Serotonin receptor
Mol File:Mol File
3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE Structure
3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE Chemical Properties
storage temp. 2-8°C
solubility H2O: 50 mg/mL
form solid
color white
Water Solubility H2O: 50mg/mL
InChI1S/C14H18N2O.C4H4O4/c1-16-6-4-10(5-7-16)13-9-15-14-3-2-11(17)8-12(13)14;5-3(6)1-2-4(7)8/h2-3,8-10,15,17H,4-7H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChIKeyINGCLXPSKXSYND-BTJKTKAUSA-N
SMILESOC(=O)\C=C/C(O)=O.CN1CCC(CC1)c2c[nH]c3ccc(O)cc23
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
WGK Germany 3
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
SigmaAldrich English
3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE Usage And Synthesis
UsesBRL 54443 Maleate Salt can be used in pharmacological activity and biological study of forskolin-free cAMP assay for Gi-coupled receptors.
Biological ActivityPotent 5-HT1E/1F serotonin receptor agonist.
in vivo

Reduction of flinching was considered as antinociception. Ipsilateral, but not contralateral, peripheral administration of BRL54443 (5-HT(1E/1F); 3-300 microg/paw) significantly reduced formalin-induced flinching in rats[3].

3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE Preparation Products And Raw materials
Tag:3-(1-METHYLPIPERIDIN-4-YL)-1H-INDOL-5-OL MALEATE(1197333-54-2) Related Product Information
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