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| | N-(4-AMinobutyl)biotinaMide Basic information |
| Product Name: | N-(4-AMinobutyl)biotinaMide | | Synonyms: | N-(4-AMinobutyl)biotinaMide;N-(4-Aminobutyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-(4-aminobutyl)hexahydro-2-oxo-, (3aS,4S,6aR)-;Biotin-C4-amide-C5-NH2;(3aS,4S,6aR)-N-(4-Aminobutyl)hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide | | CAS: | 151294-96-1 | | MF: | C14H26N4O2S | | MW: | 314.44684 | | EINECS: | | | Product Categories: | | | Mol File: | 151294-96-1.mol |  |
| | N-(4-AMinobutyl)biotinaMide Chemical Properties |
| Boiling point | 650.1±50.0 °C(Predicted) | | density | 1.148±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | pka | 13.90±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | N-(4-AMinobutyl)biotinaMide Usage And Synthesis |
| Uses | Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | | Biological Activity | Biotin-C4-amide-C5-NH2 is a cleavable ADC linker that can be used to synthesize antibody-drug conjugates (ADCs). | | in vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. | | target | | | IC 50 | Cleavable Linker | | References | [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
| | N-(4-AMinobutyl)biotinaMide Preparation Products And Raw materials |
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