| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 13211707573; |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Epimedokoreanin B
CAS:161068-53-7
Purity:97.5% Package:5mg Remarks:BBP03055
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EpiMedokoreanin B manufacturers
- Epimedokoreanin B
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- $543.00 / 10mg
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2026-05-15
- CAS:161068-53-7
- Min. Order:
- Purity: 99.75%
- Supply Ability: 10g
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| | EpiMedokoreanin B Basic information |
| Product Name: | EpiMedokoreanin B | | Synonyms: | 2-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;EpiMedokoreanin B;4H-1-Benzopyran-4-one, 2-[3,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-8-(3-methyl-2-buten-1-yl)-;Icariin Impurity 8;IcariinImpurity9;Epimedokoreanin B, 10 mM in DMSO | | CAS: | 161068-53-7 | | MF: | C25H26O6 | | MW: | 422.47 | | EINECS: | | | Product Categories: | | | Mol File: | 161068-53-7.mol |  |
| | EpiMedokoreanin B Chemical Properties |
| Boiling point | 665.9±55.0 °C(Predicted) | | density | 1.301±0.06 g/cm3(Predicted) | | form | Solid | | pka | 6.61±0.40(Predicted) | | color | Light yellow to yellow |
| | EpiMedokoreanin B Usage And Synthesis |
| Uses | Epimedokoreanin B is a natural flavonoid with anticancer, anti-inflammatory and antibacterial effects. Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated apoptosis accompanied by autophagosome accumulation. Epimedokoreanin B is an anti-periodontitis agent that inhibits gingipains and Porphyromonas gingivalis growth and biofilm formation[1][2][3]. | | in vivo | Epimedokoreanin B (20 mg/kg; p.o; thrice a week; for 17 days) inhibits tumor growth in an LM8 tumor-bearing murine model[4]. | Animal Model: | Female C3H mice (8-10 weeks old) injected with LM8 cells[4] | | Dosage: | 20 mg/kg | | Administration: | Oral administration; thrice a week; for 17 days | | Result: | Inhibited tumor growth. |
| | References | [1] Huaran Zhang, et al. Flavonoids from the leaves of Epimedium Koreanum Nakai and their potential cytotoxic activities. Nat Prod Res. 2020 May;34(9):1256-1263. DOI:10.1080/14786419.2018.1560283
[2] Hao Zheng, et al. Epimedokoreanin B inhibits the growth of lung cancer cells through endoplasmic reticulum stress-mediated paraptosis accompanied by autophagosome accumulation. Chem Biol Interact. 2022 Oct 1;366:110125. DOI:10.1016/j.cbi.2022.110125
[3] T Kariu, et al. Inhibition of gingipains and Porphyromonas gingivalis growth and biofilm formation by prenyl flavonoids. J Periodontal Res. 2017 Feb;52(1):89-96. DOI:10.1111/jre.12372
[4] Cheng Pan , et al. Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment. Front Pharmacol. 2020 Mar 18;11:262. DOI:10.3389/fphar.2020.00262 |
| | EpiMedokoreanin B Preparation Products And Raw materials |
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