2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride

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2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride manufacturers

  • GW 833972A
  • GW 833972A pictures
  • $71.00
  • 2026-07-31
  • CAS:1092502-33-4
  • Purity: 99.97%
  • Supply Ability: 10g
2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride Basic information
Product Name:2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride
Synonyms:2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride;GW833972A;2-[(3-Chlorophenyl)amino]-N-(4-pyridylmethyl)-4-(trifluoromethyl)pyrimidine-5-carboxamide Hydrochloride;GW 833972A hydrochloride - Bio-X;GW833972A >=98% (HPLC), powder;GW 833972A hydrochloride;GW 833972A, 10 mM in DMSO
CAS:1092502-33-4
MF:C18H14Cl2F3N5O
MW:444.2378696
EINECS:
Product Categories:
Mol File:1092502-33-4.mol
2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride Structure
2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride Chemical Properties
storage temp. 2-8°C
solubility DMSO: ≥20mg/mL
form powder
color off-white to light brown
InChI1S/C18H13ClF3N5O.ClH/c19-12-2-1-3-13(8-12)26-17-25-10-14(15(27-17)18(20,21)22)16(28)24-9-11-4-6-23-7-5-11;/h1-8,10H,9H2,(H,24,28)(H,25,26,27);1H
InChIKeyUBHSVFAUAKIVKL-UHFFFAOYSA-N
SMILESCl.FC(F)(F)c1nc(Nc2cccc(Cl)c2)ncc1C(=O)NCc3ccncc3
Safety Information
Hazard Codes T
Risk Statements 25-36/37/38
Safety Statements 26-45
RIDADR UN 2811 6.1 / PGIII
WGK Germany 3
Storage Class6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard ClassificationsAcute Tox. 3 Oral
Aquatic Chronic 4
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride Usage And Synthesis
UsesGW833972A, a selective CB2 cannabinoid receptor agonist, may be used separately or in comparison to other cannabinoid receptor agonist and antagonists to differentiate and characterize the CB2 cannabinoid receptor. GW833972A may be used to help verify that an observed physiological response is cannabinoid receptor CB2-dependent.
Biochem/physiol ActionsThe compound was used to determine the role of CB2 in airway sensory nerve function.
in vivo

GW 833972A (30 mg/kg, 2 mL/kg; i.p.; single dose 30 min before test) inhibits tussive response in conscious guinea pigs induced by citric acid. It also inhibits capsaicin-induced plasma protein exudation in the main bronchus[1].

IC 50hCB2-R: 7.3 (pEC50); rat CB2-R: 7.5 (pEC50)
2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride Preparation Products And Raw materials
Tag:2-[(3-chlorophenyl)amino]-N-(4-pyridinylmethyl)-4-(trifluoromethyl)-5-Pyrimidinecarboxamide hydrochloride(1092502-33-4) Related Product Information
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