IX 207-887
| 中文名称 | IX 207-887 |
|---|---|
| 中文同义词 | 化合物 T11697;化合物 IX 207-887;IX 207-887试剂;IX 207-887试剂 |
| 英文名称 | (Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID |
| 英文同义词 | IX 207-887;[10-Methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene]acetic acid;(Z)-10-METHOXY-4H-BENZO[4,5]CYCLOHEPTA[1,2-B]THIOPHENE-4-YLIDENE ACETIC ACID;Acetic acid, 2-(10-methoxy-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-;IX 207 887,IX 207887;(2Z)-2-(8-Methoxy-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,8,10,12-hexaen-2-ylidene)acetic acid |
| CAS号 | 98320-39-9 |
| 分子式 | C16H12O3S |
| 分子量 | 284.33 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 98320-39-9.mol |
| 结构式 |  |
IX 207-887 性质
| 沸点 | 475.0±45.0 °C(Predicted) |
|---|---|
| 密度 | 1.37±0.1 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 溶于二甲基亚砜 |
| 形态 | 固体 |
| 酸度系数(pKa) | 3.81±0.41(Predicted) |
| 颜色 | 浅黄至黄色 |
IX 207-887 是一种新型抗关节炎药物, 也能抑制白细胞介素-1 (IL-1) 的释放。
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IL-1
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IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed.
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-106087 | IX 207-887 | 98320-39-9 | 5 mg | 1300元 |
| 2025/12/22 | HY-106087 | IX 207-887 | 98320-39-9 | 10 mM * 1 mLin DMSO | 1430元 |