(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine

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(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Basic information
Product Name:(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine
Synonyms:Tofacitinib-4;Tofacitinib impurity 3/(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride;(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine? (Tofacitinib Impurity);Tofatinib Impurity 35;3-Piperidinamine, N,4-dimethyl-1-(phenylmethyl)-, (3R,4S)-;Tofacitinib Impurity J 2HCl;Nicotinamide Impurity 114;Tofacitinib Citrate Impurity 38
CAS:1638499-31-6
MF:C14H22N2
MW:218.34
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Mol File:1638499-31-6.mol
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Structure
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Chemical Properties
Boiling point 302.6±35.0 °C(Predicted)
density 1.00±0.1 g/cm3(Predicted)
pka10.26±0.40(Predicted)
Safety Information
MSDS Information
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Usage And Synthesis
Uses(3R,4S)-1-Benzyl-N,4-dimethylpiperidin-3-amine is an intermediate in the synthesis of (3R,4S)-Tofacitinib (T528000). (3R,4S)-Tofacitinib is an enantiopure stereoisomer of the drug, Janus kinase 3(Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine Preparation Products And Raw materials
Tag:(3R,4S)-1-benzyl-N,4-dimethylpiperidin-3-amine(1638499-31-6) Related Product Information
4-Methyl-3-methylaminopyridine Cyanoacetic acid-OSu 2,4-Dichloro-7H-pyrrolo2,3-dpyrimidine 4-chloro-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine N-((3R,4R)-1-(2-cyanoacetyl)-4-methylpiperidin-3-yl)-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine oxide 3-((3R,4R)-3-((2-chloro-7H-pyrrolo[2,3-d]pyriMidin-4-yl)(Methyl)aMino)-4-Methylpiperidin-1-yl)-3-oxopropanenitrile 3-Piperidinamine,4-methyl-1-(phenylmethyl)-,(3R,4R)-rel- Tofacitinib impurity T N-Hydroxysuccinimide 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine methyl3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin -4-yl)amino)piperidin-1-yl)-3-oxopropanoate Methyl (4-Methylpiperidin-3-yl)carbaMate 3-((3S,4R)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride 3-((3R,4S)-4-Methyl-3-(Methyl(7H-pyrrolo[2,3-d]pyriMidin-4-yl)aMino)piperidin-1-yl)-3-oxopropanenitrile 1-Piperidinepropanoic acid, 4-methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-, ethyl ester, (3R,4R)- (3R,4R)-N,4-dimethyl-piperidin-3-amine 3-((3S,4S)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile