Duvoglustat Hydrochloride manufacturers
- Ridinilazole
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- $43.00
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2026-04-22
- CAS:308362-25-6
- Purity: 98.57%
- Supply Ability: 10g
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| | Duvoglustat Hydrochloride Basic information |
| Product Name: | Duvoglustat Hydrochloride | | Synonyms: | 2,2'-di(pyridin-4-yl)-3H,3'H-5,5'-bibenzo[d]imidazole;SMT19969;5,5'-Bi-1H-benzimidazole, 2,2'-di-4-pyridinyl-;2,2'-Di(pyridin-4-yl)-1H,1'H-5,5'-bibenzo[d]imidazole;SMT 19969,inhibit,SMT-19969,Bacterial,Ridinilazole,Inhibitor;Ridinilazole, 10 mM in DMSO | | CAS: | 308362-25-6 | | MF: | C24H16N6 | | MW: | 388.42 | | EINECS: | | | Product Categories: | | | Mol File: | 308362-25-6.mol |  |
| | Duvoglustat Hydrochloride Chemical Properties |
| Boiling point | 774.9±70.0 °C(Predicted) | | density | 1.372±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : ≥ 60 mg/mL (154.47 mM) | | pka | 9.84±0.10(Predicted) | | form | Solid | | color | Light yellow to yellow | | InChI | InChI=1S/C24H16N6/c1-3-19-21(29-23(27-19)15-5-9-25-10-6-15)13-17(1)18-2-4-20-22(14-18)30-24(28-20)16-7-11-26-12-8-16/h1-14H,(H,27,29)(H,28,30) | | InChIKey | UHQFBTAJFNVZIV-UHFFFAOYSA-N | | SMILES | C1(C2C=CN=CC=2)NC2=CC=C(C3=CC=C4NC(C5C=CN=CC=5)=NC4=C3)C=C2N=1 |
| | Duvoglustat Hydrochloride Usage And Synthesis |
| Uses | Ridinilazole is a novel antibacterial with MICs range of 0.06-0.25μg/mL (MIC90=8μg/mL) against C.difficile. | | in vivo | In a hamster model of CDI with a once-daily dosing regimen, Ridinilazole displays greater efficacy than Vancomycin both against non-epidemic and epidemic strains of C.difficile. Similar to the twice-daily dosing study, plasma levels of Ridinilazole are below the level of detection, whereas caecal Ridinilazole concentrations are well above the MIC, thus demonstrating the non-absorbable nature of Ridinilazole and minimal systemic exposure[1]. | | References | [1] Vickers RJ, et al. Ridinilazole: a novel therapy for Clostridium difficile infection. Int J Antimicrob Agents. 2016 Aug;48(2):137-43. DOI:10.1016/j.ijantimicag.2016.04.026 |
| | Duvoglustat Hydrochloride Preparation Products And Raw materials |
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