| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Company Name: |
Musechem |
| Tel: |
+1-800-259-7612 |
| Email: |
info@musechem.com |
Mavoglurant (racemate) manufacturers
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| | Mavoglurant (racemate) Basic information |
| Product Name: | Mavoglurant (racemate) | | Synonyms: | Mavoglurant (racemate);AFQ-056 racemate;1H-Indole-1-carboxylic acid, octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-, methyl ester, (3aR,4S,7aR)-rel- | | CAS: | 1636881-61-2 | | MF: | C19H23NO3 | | MW: | 313.39 | | EINECS: | | | Product Categories: | | | Mol File: | 1636881-61-2.mol |  |
| | Mavoglurant (racemate) Chemical Properties |
| Melting point | 107.5-108 °C | | Boiling point | 476.3±45.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 50 mg/mL (159.55 mM) | | form | Solid | | pka | 12.75±0.20(Predicted) | | color | White to off-white |
| | Mavoglurant (racemate) Usage And Synthesis |
| Uses | Mavoglurant racemate (AFQ-056 racemate) is the racemate of Mavoglurant. Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist[1]. Mavoglurant (racemate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | mGluR5 | | References | [1] Vranesic I, et al. AFQ056/mavoglurant, a novel clinically effective mGluR5 antagonist: identification, SAR and pharmacological characterization. Bioorg Med Chem. 2014 Nov 1;22(21):5790-80 DOI:10.1016/j.bmc.2014.09.033 |
| | Mavoglurant (racemate) Preparation Products And Raw materials |
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