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| | m-PEG7-4-nitrophenyl carbonate Basic information |
| Product Name: | m-PEG7-4-nitrophenyl carbonate | | Synonyms: | m-PEG7-4-nitrophenyl carbonate;2,5,8,11,14,17,20-Heptaoxaheneicosanoic acid, 4-nitrophenyl ester;inhibit,PROTAC Linkers,m PEG7 4 nitrophenyl carbonate,m-PEG-7-4-nitrophenyl carbonate,mPEG74nitrophenyl carbonate,Inhibitor | | CAS: | 678150-56-6 | | MF: | C20H31NO11 | | MW: | 461.46 | | EINECS: | | | Product Categories: | | | Mol File: | 678150-56-6.mol |  |
| | m-PEG7-4-nitrophenyl carbonate Chemical Properties |
| form | Liquid | | color | Colorless to light yellow |
| | m-PEG7-4-nitrophenyl carbonate Usage And Synthesis |
| Description | m-PEG7-4-nitrophenyl carbonate is a PEG linker with a nitrophenyl carbonate group. The nitrophenyl carbonate is a good leaving group and can react with the amine groups of lysine residue by forming a stable urethan linkage. | | Uses | m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | m-PEG7-4-nitrophenyl carbonate Preparation Products And Raw materials |
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