羟基香豆素
| 中文名称 | 羟基香豆素 |
|---|---|
| 中文同义词 | 羟基香豆素;(±)-5-乙基-5-(4-羟苯基)-3-甲基海因;(±)-5-乙基-5-(4-羟苯基)-3-甲基羟基香豆素-2,4-二酮;(+/-)-4'-羟基美芬妥英;4羟基美芬妥英;3-甲基-5-乙基-5-(4-羟基苯基)-2,4-咪唑烷二酮;美芬妥英杂质1;(+/-)-4-HYDROXY MEPHENYTOIN |
| 英文名称 | 4-HYDROXY MEPHENYTOIN |
| 英文同义词 | (+/-) -HYDROXYMEPHENYTOIN;5-Ethyl-5-(4-hydroxyphenyl)-3-Methyl-;(±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylhydantoin, (±)-5-Ethyl-5-(4-hydroxyphenyl)-3-methylimididazolidine-2,4-dione;4-Hydroxy-5-ethyl-3-methyl-5-phenylimidazolidin-2-one;4'-Hydroxymephenitoyn;5-(p-Hydroxyphenyl)-3-methyl-5-ethyl-imidazolidine-2,4-dione;5-Ethyl-3-methyl-5-(4-hydroxyphenyl)hydantoin;5-Ethyl-3-methyl-5-(4-hydroxyphenyl)imidazolidine-2,4-dione |
| CAS号 | 61837-65-8 |
| 分子式 | C12H14N2O3 |
| 分子量 | 234.25 |
| EINECS号 | |
| 相关类别 | 体外研究产品-体外代谢标准品;Chemical Synthesis;Heterocyclic Building Blocks;Imidazolines/Imidazolidines;Metabolites;Heterocycles;Hydantoins & Derivatives;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Building Blocks |
| Mol文件 | 61837-65-8.mol |
| 结构式 |  |
羟基香豆素 性质
| 熔点 | 153-154 °C |
|---|---|
| 密度 | 1.249±0.06 g/cm3(Predicted) |
| 储存条件 | 2-8°C |
| 溶解度 | 二甲基亚砜：>5mg/mL |
| 酸度系数(pKa) | 8.31±0.70(Predicted) |
| 形态 | 固体 |
| 颜色 | 白色 |
| InChI | 1S/C12H14N2O3/c1-3-12(8-4-6-9(15)7-5-8)10(16)14(2)11(17)13-12/h4-7,15H,3H2,1-2H3,(H,13,17) |
| InChIKey | OQPLORUDZLXXPD-UHFFFAOYSA-N |
| SMILES | CCC1(NC(=O)N(C)C1=O)c2ccc(O)cc2 |
4-Hydroxymephenytoin 是抗癫痫药 mephenytoin 的代谢物; mephenytoin 为 CYP2C19 的一种配体。
4-Hydroxymephenytoin is a metabolism of mephenytoin, which is an antiepileptic drug, and used as a CYP2C19 substrate. 4-Hydroxymephenytoin (4'-Hydroxymephenytoin) is used for developing UltraPerformance LC (UPLC) tandem mass spectrometry assays for evaluating CYP probe drugs and their relevant metabolites in human urine or plasma samples.
安全信息
| WGK Germany | 3 |
|---|---|
| 存储类别 | 11 - 可燃固体 |
| 提供商 | 语言 |
|---|---|
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英文
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| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-W008772 | 羟基香豆素 4-Hydroxymephenytoin | 61837-65-8 | 1mg | 800元 |
| 2026/06/05 | HY-W008772R | 羟基香豆素 4-Hydroxymephenytoin (Standard) | 61837-65-8 | 5 mg | 6000元 |