2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride

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2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride Basic information
Product Name:2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride
Synonyms:NTNCB HYDROCHLORIDE;Benzenesulfonamide, 2-nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]-;2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride
CAS:486453-65-0
MF:C25H33N3O4S
MW:471.61
EINECS:
Product Categories:Neuropeptide Y (NPY ) receptor
Mol File:486453-65-0.mol
2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride Structure
2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride Chemical Properties
Boiling point 638.407±61.00 °C(Press: 760.00 Torr)(predicted)
density 1.200±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Store at RT
pka10.330±0.10(predicted)
Safety Information
MSDS Information
2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride Usage And Synthesis
UsesNTNCB Hydrochloride was used to study DNA encodoing a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5).
Biological ActivitySelective, non-peptide competitive NPY Y 5 antagonist. K i values are 8.0 and 16032 nM at human recombinant Y 5 and Y 1 receptors respectively. Potently antagonizes NPY inhibition of forskolin-stimulated cAMP. Displays some affinity for cloned human D 2 and α 2C receptors (K i values are 63 and 100 nM respectively).
2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride Preparation Products And Raw materials
Tag:2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride(486453-65-0) Related Product Information
2-Nitro-N-[[trans-4-[[[(1,2,3,4-tetrahydro-2-naphthalenyl)methyl]amino]methyl]cyclohexyl]methyl]benzenesulfonamide hydrochloride 1-Amino-6-(2-nitrobenzenesulfonamido)hexane hydrochloride