| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Zaragozic acid C
CAS:146389-62-0
Package:25mg/RMB 49100;100mg/RMB 87500;50mg/RMB 66300
|
|
| | zaragozic acid C Basic information |
| Product Name: | zaragozic acid C | | Synonyms: | 350;L 697350;L697350;L-697350;L-erythro-L-glycero-D-altro-7-Trideculo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13-pentadeoxy-12-(phenylmethyl)-, 11-acetate 5-[(4E,6R)-6-methyl-9-phenyl-4-nonenoate], (7S)- | | CAS: | 146389-62-0 | | MF: | C40H50O14 | | MW: | 754.8166 | | EINECS: | | | Product Categories: | | | Mol File: | 146389-62-0.mol |  |
| | zaragozic acid C Chemical Properties |
| alpha | D20 +9.6° (c = 0.29 in ethanol) | | Boiling point | 898.3±65.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | pka | 1.49±0.70(Predicted) |
| | zaragozic acid C Usage And Synthesis |
| Uses | Zaragozic acid C (L-697350) is a potent sterol synthase inhibitor with potential antitumor activity. Zaragozic acid C contains multiple hydroxyl and alkyl substituents in its chemical structure, demonstrating complex functionalization capabilities. The synthesis of zaragozic acid C involves a photochemical C(sp3)-H acylation reaction, which resolves the challenging carbon substitution problem in the synthesis[1]. | | Definition | ChEBI: Zaragozic acid C is a polyketide isolated from fungi that is a potent inhibitor of fungal and mammalian squalene synthase. It has a role as an EC 2.5.1.21 (squalene synthase) inhibitor and a fungal metabolite. It is an acetate ester, a cyclic ketal, an oxabicycloalkane, a polyketide, a tertiary alcohol and a tricarboxylic acid. | | References | [1] Total Synthesis of Zaragozic Acid C: Implementation of Photochemical C(sp3)-H Acylation DOI:10.1021/jacs.6b13263 |
| | zaragozic acid C Preparation Products And Raw materials |
|