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| | Zaragozic acid D Basic information |
| Product Name: | Zaragozic acid D | | Synonyms: | Zaragozic acid D;L-glycero-D-altro-Pentadec-14-en-7-ulo-7,4-furanosonic acid, 2,7-anhydro-3,4-di-C-carboxy-8,9,10,12,13,14,15-heptadeoxy-12-methyl-15-phenyl-, 11-acetate 5-octanoate, (7S,11ξ,12ξ,14E)- | | CAS: | 155179-14-9 | | MF: | C34H46O14 | | MW: | 678.72 | | EINECS: | | | Product Categories: | | | Mol File: | 155179-14-9.mol |  |
| | Zaragozic acid D Chemical Properties |
| Boiling point | 821.7±65.0 °C(Predicted) | | density | 1.35±0.1 g/cm3(Predicted) | | pka | 1.50±0.70(Predicted) |
| | Zaragozic acid D Usage And Synthesis |
| Uses | Zaragozic acid D is a squalene synthase inhibitor. Zaragozic acid D also is a farnesyl-protein transferase (FPTase) inhibitor with an IC50 value of 100 nM for bovine FPTase[1][2]. | | References | [1] Leeyuan Huang, et al. New fungal metabolites as potential antihypercholesterolemics and anticancer agents. Canadian Journal of Botany, 1995, 73(S1): 898-906.
[2] Dufresne C, et al. Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase. J Nat Prod. 1993 Nov;56(11):1923-9. DOI:10.1021/np50101a009 |
| | Zaragozic acid D Preparation Products And Raw materials |
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