H-Lys-Arg-Thr-Leu-Arg-Arg-OH

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H-Lys-Arg-Thr-Leu-Arg-Arg-OH Basic information
Product Name:H-Lys-Arg-Thr-Leu-Arg-Arg-OH
Synonyms:LYS-ARG-THR-LEU-ARG-ARG;LYS-ARG-THR-LEU-ARG-ARG TRIFLUOROACETATE SALT;KRTLRR;EPIDERMAL GROWTH FACTOR RECEPTOR (HUMAN) (652-657);EGF RECEPTOR (HUMAN) (652-657);PROTEIN KINASE C IN PC12 PHEOCHROMOCYTOM;PROTEIN KINASE C SUBSTRATE KRTLRR;lys-arg-thr-leu-arg-arg*trifluoroacetate
CAS:121284-21-7
MF:C34H68N16O8
MW:829.01
EINECS:
Product Categories:peptide;Enzyme Substrates;Protein Kinase C (PKC)Peptides for Cell Biology;Protein Kinase CSerine/Threonine Kinase Biology;Protein Kinase Related Peptides;Protein Kinase Substrates;Serine/Threonine Kinase Substrates;Substrates by Enzyme
Mol File:121284-21-7.mol
H-Lys-Arg-Thr-Leu-Arg-Arg-OH Structure
H-Lys-Arg-Thr-Leu-Arg-Arg-OH Chemical Properties
density 1.46±0.1 g/cm3(Predicted)
storage temp. −20°C
pka3.31±0.10(Predicted)
SequenceLys-Arg-Thr-Leu-Arg-Arg
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
H-Lys-Arg-Thr-Leu-Arg-Arg-OH Usage And Synthesis
UsesLys-Arg-Thr-Leu-Arg-Arg (KRTLRR) is a hexapeptide. Lys-Arg-Thr-Leu-Arg-Arg is a substrate of protein kinase C from EGF receptor. Lys-Arg-Thr-Leu-Arg-Arg can be used to determine the activity of protein kinase C[1].
References[1] Davis RJ, et, al. Stimulation of epidermal growth factor receptor threonine 654 phosphorylation by platelet-derived growth factor in protein kinase C-deficient human fibroblasts. J Biol Chem. 1987 May 15;262(14):6832-41. PMID:3106361
H-Lys-Arg-Thr-Leu-Arg-Arg-OH Preparation Products And Raw materials
Tag:H-Lys-Arg-Thr-Leu-Arg-Arg-OH(121284-21-7) Related Product Information
PKC β pseudosubstrate PROTEIN KINASE C (19-31) ZIP AKT/SKG SUBSTRATE PEPTIDE HATPPKKKRK QKRPRRKDTP H-Leu-Leu-Tyr-Glu-Met-Leu-Ala-Gly-Gln-Ala-Pro-Phe-Glu-Gly-Glu-Asp-Glu-Asp-Glu-Leu-Phe-Gln-Ser-Ile-Met-Glu-His-Asn-Val-NH2 H-Val-Arg-Lys-Arg-Thr-Leu-Arg-Arg-Leu-OH H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn-OH Plsrtlsvaakk-NH2 H-Arg-Lys-Arg-Ser-Arg-Ala-Glu-OH H-Lys-Arg-Thr-Leu-Arg-Arg-OH H-Arg-Arg-OH acetate salt Epidermal Growth Factor