3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one

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3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one manufacturers

  • KSI-3716
  • KSI-3716 pictures
  • 2026-07-27
  • CAS:1151813-61-4
  • Purity: 98.94%
  • Supply Ability: 10g
3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one Basic information
Product Name:3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one
Synonyms:3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one;KSI-3716;4(1H)-Quinolinone, 3-acetyl-8-bromo-5-chloro-2-[(4-chlorophenyl)amino]-;KSI 3716,KSI3716
CAS:1151813-61-4
MF:C17H11BrCl2N2O2
MW:426.09
EINECS:
Product Categories:
Mol File:1151813-61-4.mol
3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one Structure
3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one Chemical Properties
Boiling point 532.8±50.0 °C(Predicted)
density 1.675±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 5 mg/mL (11.73 mM)
pka-2.74±0.20(Predicted)
form Solid
color Light yellow to khaki
Safety Information
MSDS Information
3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one Usage And Synthesis
UsesKSI-3716 is a potent c-Myc inhibitor that blocks c-MYC/MAX binding to target gene promoters. KSI-3716 is an effective intravesical chemotherapy agent for bladder cancer[1].
in vivo

Intravesical instillation of KSI-3716 at a dose of 5 mg/kg significantly suppresses tumor growth with minimal systemic toxicity[1].

References[1] Jeong KC, et al. Intravesical instillation of c-MYC inhibitor KSI-3716 suppresses orthotopic bladder tumor growth. J Urol. 2014 Feb;191(2):510-8. DOI:10.1016/j.juro.2013.07.019
3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one Preparation Products And Raw materials
Tag:3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one(1151813-61-4) Related Product Information
3-acetyl-8-bromo-5-chloro-2-(4-chloroanilino)-1H-quinolin-4-one 4(1H)-Quinolinone, 3-acetyl-5,8-dichloro-2-[(2,4-dichlorophenyl)amino]- 1H-Benzimidazole-2-methanamine, N-[[3-ethoxy-4-(2-thienylmethoxy)phenyl]methyl]- Fucoxanthin agrimol B RS47