| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
N-[(1-Butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide manufacturers
- Nafadotride
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- $1980.00
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2026-05-11
- CAS:149649-22-9
- Purity:
- Supply Ability: 10g
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| | N-[(1-Butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide Basic information |
| | N-[(1-Butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide Chemical Properties |
| Boiling point | 556.6±40.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | storage temp. | Desiccate at RT | | pka | 12.84±0.46(Predicted) |
| | N-[(1-Butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide Usage And Synthesis |
| Uses | Nafadotride is a highly potent and competitive dopamine D3 receptor (D3R) antagonist. | | Definition | ChEBI: A naphthalenecarboxamide resulting from the formal condensation of the carboxylic acid group of 4-cyano-1-methoxynaphthalene-2-carboxylic acid with the primary amino group of 1-(1-butylpyrrolidin-2-yl]methanamine. It is a highly potent, competitive, prefer
ntial dopamine D3 receptor antagonist, centrally active upon systemic administration. | | Biological Activity | Highly potent, competitive, preferential dopamine D 3 receptor antagonist. K i values are 0.52, 5, and 269 nM for human cloned D 3 , D 2 and D 4 receptors respectively. Centrally active upon systemic administration. |
| | N-[(1-Butyl-2-pyrrolidinyl)methyl]-4-cyano-1-methoxy-2-naphthalenecarboxamide Preparation Products And Raw materials |
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