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| | D-[ul-13C6]Fructose Basic information |
| | D-[ul-13C6]Fructose Chemical Properties |
| Melting point | 119-122 °C (dec.) (lit.) | | storage temp. | Store at -20°C | | solubility | DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid | | color | White to off-white | | Optical Rotation | [α]20/D -93.5°, c = 2 in H2O (trace NH4OH) | | InChI | 1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1 | | InChIKey | BJHIKXHVCXFQLS-HJLYHLTLSA-N | | SMILES | O[13CH2][13C@@H](O)[13C@@H](O)[13C@H](O)[13C](=O)[13CH2]O | | CAS Number Unlabeled | 57-48-7 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | D-[ul-13C6]Fructose Usage And Synthesis |
| Description | D-Fructose-13C6 is intended for use as an internal standard for the quantification of D-fructose by GC- or LC-MS. D-Fructose is a ubiquitous monosaccharide and is derived, in addition to glucose, from the breakdown of sucrose by sucrase in the intestine. It is a precursor in the biosynthesis of D-fructose-1,6-bisphosphate , which is an intermediate in the production of D-glucose via gluconeogenesis. Deficiencies in the enzymes that metabolize D-fructose are inborn errors of metabolism that range from benign, for fructokinase deficiency, to severe, for hereditary fructose intolerance, if D-fructose, sucrose, and sorbitol are not eliminated from the diet. Increased consumption of D-fructose is associated with obesity, dyslipidemia, and impaired insulin sensitivity. | | Uses | Isotope labelled D-Fructose (F792500), a monosaccharide that naturally occurs in large number of fruits and plants. | | References | [1] M CHEN R L W. Metabolism of D-fructose.[J]. Advances in carbohydrate chemistry and biochemistry, 1977, 34: 265-343.
[2] TRAN C. Inborn Errors of Fructose Metabolism. What Can We Learn from Them[J]. Nutrients, 2017, 9 4. DOI: 10.3390/nu9040356
[3] LUC TAPPY Kim A L. Metabolic effects of fructose and the worldwide increase in obesity.[J]. Physiological reviews, 2010, 90 1: 23-46. DOI: 10.1152/physrev.00019.2009 |
| | D-[ul-13C6]Fructose Preparation Products And Raw materials |
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