| Company Name: |
Biolab Reagents |
| Tel: |
027-65279366 18108604356 |
| Email: |
products@biolabreagent.com |
| Company Name: |
ACROBiosystems |
| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
|
| | ANTI-BCL-X Basic information |
| Product Name: | ANTI-BCL-X | | Synonyms: | Anti-BCL2L1 antibody produced in chicken;Anti-BCL2L1, (N-terminal) antibody produced in rabbit;BCL-X (AB-1) POLYCLONAL ANTIBODY;Anti-Bcl-x antibody produced in rabbit;Anti-BCL-XL antibody produced in rabbit;Anti-BCL2L1 antibody produced in rabbit;Monoclonal Anti-BCL2L1 antibody produced in mouse;ANTI-HUMAN/MOUSE BCL-2-LIKE 1 AA 49 - 68 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | Elisa Kit-Rat Elisa Kit | | Mol File: | Mol File | ![ANTI-BCL-X Structure]() |
| | ANTI-BCL-X Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | 2 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Eye Irrit. 2
Repr. 1B
Skin Irrit. 2 |
| | ANTI-BCL-X Usage And Synthesis |
| Uses | Useful for the study of apoptosis, screening inhibitors, and selectivity profiling. | | Biological Activity | BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators th at are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. |
| | ANTI-BCL-X Preparation Products And Raw materials |
|