N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester

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N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester Basic information

Product Name:	N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester
Synonyms:	methyl 3-phenyl-2-(pyrazine-2-carbonylamino)propanoate;Bortezomib Acid Methyl Ester;Bortezomib Impurity R;(S)-methyl 3-phenyl-2-(pyrazine-2-carboxamido)propanoate;Bortezomib Imp.F;N-PYRAZINYLCARBONYLPHENYLALANINE METHYL ESTER;3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester;N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester
CAS:	73058-37-4
MF:	C15H15N3O3
MW:	285.3
EINECS:
Product Categories:	Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Aromatics
Mol File:	73058-37-4.mol

N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester Chemical Properties

Melting point	55 °C
Boiling point	533.2±50.0 °C(Predicted)
density	1.238±0.06 g/cm3(Predicted)
storage temp.	-20°C Freezer
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	11.75±0.46(Predicted)
color	Pale Yellow to Light Yellow

Safety Information

MSDS Information

N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester Usage And Synthesis

Chemical Properties	Yellow Oil
Uses	N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester can be used for the synthesis of Bortezomib from L-phenylalanine via dipeptidyl boronic acid ester intermediates.

N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester Preparation Products And Raw materials

Preparation Products

Tag:N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester(73058-37-4) Related Product Information

Desisobutyl-n-butyl BortezoMib Bortezomib Impurity 32 4,6-Methano-1,3,2-benzodioxaborole-2-MethanaMine,hexahydro-3a,5,5-triMethyl-a-(2-Methylpropyl)-N,N-bis(triMethylsilyl)-,(aR,3aS,4S,6S,7aR)- Acetamide, 2-amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]- Bortezomib Impurity 60 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine 4,6-Methano-1,3,2-benzodioxaborole,2-[(1S)-1-chloro-3-Methylbutyl]hexahydro-3a,5,5-triMethyl-,(3aS,4S,6S,7aR)- Isovaleraldehyde Bortezomib Impurity 9 Bortezomib Impurity 52 3,6-Dibenzylhexahydropyrazine-2,5-dione Bortezomib intermediates II 4,6-Methano-1,3,2-benzodioxaborole, hexahydro-3a,5,5-trimethyl-2-(3-methylbutyl)-, [3aS-(3aα,4β,6β,7aα)]- (9CI) (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid (1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Bortezomib Impurity 57 H-Phe-Phe-OH (S)-(+)-Pinanediol (dichlormethyl)boronate

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