| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
GW284543 manufacturers
- GW284543
-
- $30.00
-
2026-04-22
- CAS:790186-68-4
- Purity: 99.75%
- Supply Ability: 10g
|
| | GW284543 Basic information |
| Product Name: | GW284543 | | Synonyms: | GW284543;GW284543 (UNC10225170);UNC10225170;4-Quinolinamine, 6,7-dimethoxy-N-(3-phenoxyphenyl)-;6,7-Dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine;Inhibitor,inhibit,GW 284543,GW284543,UNC 10225170,MIA PaCa-2,GW-284543,Mitogen-activated protein kinase kinase,MEK,MAPKK,UNC-10225170,MAP2K;GW284543 HCl;GW284543, 10 mM in DMSO | | CAS: | 790186-68-4 | | MF: | C23H20N2O3 | | MW: | 372.42 | | EINECS: | | | Product Categories: | | | Mol File: | 790186-68-4.mol |  |
| | GW284543 Chemical Properties |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO:67.0(Max Conc. mg/mL);179.9(Max Conc. mM) | | form | Solid | | color | Off-white to gray |
| | GW284543 Usage And Synthesis |
| Uses | GW284543 (UNC10225170) is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein[1]. | | IC 50 | MEK5 | | References | [1] Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. DOI:10.1016/j.ccell.2018.10.001 |
| | GW284543 Preparation Products And Raw materials |
|