GW 284543 hydrochloride - UNC 10225170 hydrochloride

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GW 284543 hydrochloride - UNC 10225170 hydrochloride manufacturers
GW 284543 hydrochloride - UNC 10225170 hydrochloride Basic information
Product Name:GW 284543 hydrochloride - UNC 10225170 hydrochloride
Synonyms:GW 284543 hydrochloride - UNC 10225170 hydrochloride;GW 284543 hydrochloride;6,7-Dimethoxy-N-(3-phenoxyphenyl)quinolin-4-amine hydrochloride;W 284543 hydrochloride
CAS:179246-08-3
MF:C23H21ClN2O3
MW:408.88
EINECS:
Product Categories:
Mol File:179246-08-3.mol
GW 284543 hydrochloride - UNC 10225170 hydrochloride Structure
GW 284543 hydrochloride - UNC 10225170 hydrochloride Chemical Properties
storage temp. Sealed in dry,Room Temperature
Safety Information
MSDS Information
GW 284543 hydrochloride - UNC 10225170 hydrochloride Usage And Synthesis
UsesGW284543 (UNC10225170) hydrochloride is a selective MEK5 inhibitor. GW284543 reduces pERK5, and decreases endogenous MYC protein[1].
IC 50MEK5
References[1] Vaseva AV, et al. KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism. Cancer Cell. 2018 Nov 12;34(5):807-822.e7. DOI:10.1016/j.ccell.2018.10.001
GW 284543 hydrochloride - UNC 10225170 hydrochloride Preparation Products And Raw materials
Tag:GW 284543 hydrochloride - UNC 10225170 hydrochloride(179246-08-3) Related Product Information
5-[3-Methoxy-4-(4-methoxy-benzyloxy)-benzyl]-pyrimidine-2,4-diamine GW9508 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]- GW284543 GW788388 GW9662 GW441756 GW5074