O-(2-azidoethyl)-L-tyrosine Hydrochloride

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O-(2-azidoethyl)-L-tyrosine Hydrochloride Basic information
Product Name:O-(2-azidoethyl)-L-tyrosine Hydrochloride
Synonyms:O-(2-azidoethyl)-L-tyrosine Hydrochloride;H-L-Tyr(2-azidoethyl)-OH;H-Phe(4-(2-azidoethoxy))-OH;(S)-2-amino-3-(4-(2-azidoethoxy)phenyl)propanoic acid
CAS:1570523-47-5
MF:C11H14N4O3
MW:250.26
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Mol File:1570523-47-5.mol
O-(2-azidoethyl)-L-tyrosine Hydrochloride Structure
O-(2-azidoethyl)-L-tyrosine Hydrochloride Chemical Properties
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MSDS Information
O-(2-azidoethyl)-L-tyrosine Hydrochloride Usage And Synthesis
UsesH-L-Tyr(2-azidoethyl)-OH is a unnatural Tyrosine derivative. H-L-Tyr(2-azidoethyl)-OH is a click chemistry reagent containing an azide group[1][2]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
References[1] Tookmanian EM, et al. Azidoethoxyphenylalanine as a Vibrational Reporter and Click Chemistry Partner in Proteins. Chemistry. 2015 Dec 21;21(52):19096-103. DOI:10.1002/chem.201503908
[2] Maza JC, et al. Synthesis and Incorporation of Unnatural Amino Acids To Probe and Optimize Protein Bioconjugations. Bioconjug Chem. 2015 Sep 16;26(9):1884-9. DOI:10.1021/acs.bioconjchem.5b00424
O-(2-azidoethyl)-L-tyrosine Hydrochloride Preparation Products And Raw materials
Tag:O-(2-azidoethyl)-L-tyrosine Hydrochloride(1570523-47-5) Related Product Information
1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester MC-Val-Cit-PAB DBCO-C6-NHS ester Maleimide-DOTA Mal-PEG2-NHS ester DBCO-NHS Ester