Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxy-
| 中文名称 | Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxy- |
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| 中文同义词 | 去铁胺-马来酰亚胺;N4-[5-[[4-[[5-(ACETYLHYDROXYAMINO)PENTYL]AMINO]-1,4-DIOXOBUTYL]HYDROXYAMINO]PENTYL]-N1-[5-[[3-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-1-OXOPROPYL]AMINO]PENTYL]-N1-HYDROXYBUTANEDIAMIDE;DEFEROXAMINE-马来酰亚胺;MAL-DFO |
| 英文名称 | Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxy- |
| 英文同义词 | Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxy-;Deferoxamine-maleimide;N4-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxybutanediamide;maleimidopropionate-desferrioxamine;N-(3,11,14,22,25,33-hexaoxo-4,10,15,21,26,32-hexaaza-10,21,32- trihydroxytetratriacontane)maleimide;Mal-DFOB |
| CAS号 | 1638156-31-6 |
| 分子式 | C32H53N7O11 |
| 分子量 | 711.8 |
| EINECS号 | |
| 相关类别 | 大环化合物 |
| Mol文件 | 1638156-31-6.mol |
| 结构式 | ![Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxy- 结构式](CAS/20200331/GIF/1638156-31-6.gif) |
Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxy- 性质
| 熔点 | 180 - 182°C |
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| 密度 | 1.279±0.06 g/cm3(Predicted) |
| 储存条件 | -20°C Freezer, Under inert atmosphere |
| 溶解度 | 可溶于DMSO（少许）、甲醇（少许） |
| 形态 | 固体 |
| 酸度系数(pKa) | 9.12±0.50(Predicted) |
| 颜色 | 白色至类白色 |
Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-[5-[[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]pentyl]-N1-hydroxy- 用途与合成方法
Mal-Deferoxamine 是一种带有马来酰胺 (Mal) 的 Deferoxamine (HY-B1625)。Mal 通过选择性地与硫基共价结合，发生连接反应。Mal-Deferoxamine 通过与放射性核素结合，可合成放射性核素药物结合物 (RDC)。RDC 具有特定靶向生物分子的能力，可应用于医疗成像或治疗。